Evidence map›Paper›PMID 35528727›Full record

ArticleJournal of kidney cancer and VHL2022

High Levels of PD-L1

Sergei Kusmartsev, Elizabeth Kwenda, Paul R Dominguez-Gutierrez, Paul L Crispen, Padraic O'Malley

Open access · diamondAbstract read
In one paragraph

Article in Journal of kidney cancer and VHL, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Metastasis-promoting functions of myeloid cells.Cancer metastasis reviews · 2025
    Review
  3. Article
  4. Sesame Seeds: A Nutrient-Rich Superfood.Foods (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sergei KusmartsevDepartment of Urology, University of Florida, Gainesville, FL, USA.
Elizabeth KwendaDepartment of Urology, University of Florida, Gainesville, FL, USA.
Paul R Dominguez-GutierrezDepartment of Urology, University of Florida, Gainesville, FL, USA.
Paul L CrispenDepartment of Urology, University of Florida, Gainesville, FL, USA.
Padraic O'MalleyDepartment of Urology, University of Florida, Gainesville, FL, USA.
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) patients frequently have increased number of immunosuppressive myeloid cells in circulation. High number of myeloid-derived suppressor cells (MDSCs) in the blood are associated with immune suppression as well as with cancer-related inflammation which drives the mobilization of myeloid cells to tumor tissue. Here, we show that peripheral blood from a previously untreated RCC patient has increased the number of monocytic CD33

Indexed as

cancer immune microenvironmentHyal2myeloid-derived suppressor cellsrenal cell carcinoma

Identifiers

PMID35528727
PMCPMC9021011
OpenAlexW4224091256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.