Evidence map›Paper›PMID 35528635›Full record

ArticleJournal of environmental and public health2022

First Identification of Reinfection by a Genetically Different Variant of SARS-CoV-2 in a Homeless Person from the Metropolitan Area of Santiago, Chile.

Claudio Acuña-Castillo, Mabel Vidal, Ailen Inostroza-Molina, Eva Vallejos-Vidal, Roberto Luraschi, Maximiliano Figueroa, Carlos Barrera-Avalos, Rodrigo Vera, Sergio Vargas, Daniel Valdes and 11 more

Abstract read
In one paragraph

Article in Journal of environmental and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Claudio Acuña-CastilloCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0003-3607-6077
Mabel VidalDepartment of Computer Science, University of Concepcion, Concepción 4070409, Chile.
Ailen Inostroza-MolinaCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Eva Vallejos-VidalCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0002-3091-2700
Roberto LuraschiCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0001-5611-4320
Maximiliano FigueroaCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Carlos Barrera-AvalosCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0001-6160-9563
Rodrigo VeraHospital de Urgencia Asistencia Pública (HUAP), Santiago, Sección Biología Molecular, Laboratorio Clínico HUAP, Chile.ORCID 0000-0001-9032-7194
Sergio VargasHospital de Urgencia Asistencia Pública (HUAP), Santiago, Sección Biología Molecular, Laboratorio Clínico HUAP, Chile.
Daniel ValdesCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Kevin MaiseyCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0002-7423-6329
Mónica ImaraiCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0001-8767-9180
Elías Leiva-SalcedoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Alejandro EscobarLaboratorio Biología Celular y Molecular, Instituto de Investigación en Ciencias Odontológicas, Facultad de Odontología, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-1587-4179
Sebastián Reyes-CerpaCentro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Santiago, Chile.ORCID 0000-0002-7676-1266
Alexis GaeteLaboratorio de Bioinformática y Expresión Génica, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago, Chile.
Ricardo Palma-VejaresCentro de Modelamiento Matemático UMI-CNRS 2807, Facultad de Ciencias Físicas y Matemáticas, Universidad de Chile, Santiago, Chile.
Dante TravisanyFondap Center for Genome Regulation, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-2545-176X
Leonel E RojoCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0002-0188-2266
Felipe E Reyes-LópezCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0002-5001-457X
Ana María SandinoCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.ORCID 0000-0002-3862-3743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification and tracking of SARS-CoV-2 infected patients in the general population are essential components of the global strategy to limit the COVID-19 viral spread, specifically for maintaining traceability and suppressing the resurgence of local outbreaks. Public health programs that include continuous RT-qPCR testing for COVID-19 in the general population, viral sequencing, and genomic surveillance for highly contagious forms of the virus have allowed for the identification of SARS-CoV-2 infections and reinfections. This work identified SARS-CoV-2 reinfection in a homeless person, which occurred 58 days after the first COVID-19 diagnosis. Genomic sequencing identified a different Nextstrain classification clade (20A and 20B) and PANGO lineage, with a divergence of 4 single nucleotide variants (SNVs) in S and ORF1ab genes, suggesting reinfection by different viral variants. This study is the first from the great metropolitan area of Santiago, Chile, one of the top ten countries in the world to live during the COVID-19 pandemic. We support the importance of performing intensive genomic surveillance programs in the whole population and high-risk groups, such as homeless people, nearly 20 thousand people in Chile, and have limited access to health care services and poor viral traceability.

Indexed as

COVID-19Ill-Housed PersonsChileCOVID-19 TestingHumansPandemicsReinfectionSARS-CoV-2

Identifiers

PMID35528635
PMCPMC9068328

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.