Evidence map›Paper›PMID 35528522›Full record

ArticleOxidative medicine and cellular longevity2022

Sevoflurane Improves Hemorrhagic Shock and Resuscitation-Induced Cognitive Impairments and Mitochondrial Dysfunctions through SIRT1-Mediated Autophagy.

Jianwei Shu, Xiaotong Huang, Qizhi Liao, Jianan Wang, Yuqi Zhou, Yihuan Chen, Ming Chen, Cheng Qian, Ye Zhang, Xianwen Hu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Enhancement of CaNeuroscience bulletin · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. The duration-dependent and sex-specific effects of neonatal sevoflurane exposure on cognitive function in rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jianwei ShuDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.ORCID https://orcid.org/0000-0001-5928-8473
Xiaotong HuangDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.ORCID https://orcid.org/0000-0003-0262-3562
Qizhi LiaoDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.ORCID https://orcid.org/0000-0003-1311-400X
Jianan WangDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.
Yuqi ZhouThe Second Clinical Medical College of Anhui Medical University, Hefei City, Anhui Province, China.
Yihuan ChenThe Second Clinical Medical College of Anhui Medical University, Hefei City, Anhui Province, China.
Ming ChenThe Second Clinical Medical College of Anhui Medical University, Hefei City, Anhui Province, China.
Cheng QianCenter for Scientific Research of Anhui Medical University, Hefei City, Anhui Province, China.
Ye ZhangDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.
Xianwen HuDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.ORCID https://orcid.org/0000-0002-8342-8162
Chunxia HuangDepartment of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, China.ORCID https://orcid.org/0000-0002-1608-1226
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral ischemia reperfusion injury (IRI) induced by hemorrhagic shock and reperfusion (HSR) is the main cause of death following trauma. Previous studies indicated the neuroprotective effect of sevoflurane postconditioning (SP) in cerebral IRI. However, the mechanisms still remain elusive. Cerebral IRI models with SP were established by using HSR with C57BL/6 mice (male, 3-month-old)

Indexed as

Cognitive DysfunctionReperfusion InjuryShock, HemorrhagicAnimalsApoptosisAutophagyMaleMiceMice, Inbred C57BLMitochondriaSevofluraneSirtuin 1SevofluraneSirt1 protein, mouseSirtuin 1

Identifiers

PMID35528522
PMCPMC9068312
OpenAlexW4220883160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.