Evidence map›Paper›PMID 35528515›Full record

ArticleOxidative medicine and cellular longevity2022

Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis.

Xuan Shi, Lina Zhu, Sheng Wang, Wanli Zhu, Quanfu Li, Juan Wei, Di Feng, Meiyun Liu, Yuanli Chen, Xuejun Sun and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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  12. Nanoparticulate MgHMolecular pain
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xuan ShiDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Lina ZhuDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Sheng WangDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Wanli ZhuDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Quanfu LiDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Juan WeiDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Di FengDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Meiyun LiuDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0001-7631-4266
Yuanli ChenDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Xuejun SunDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Hongtao LuDepartment of Naval Medicine, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-0414-5798
Xin LvDepartment of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-3352-7162
Tongji University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) causes uncontrolled pulmonary inflammation, resulting in high morbidity and mortality in severe cases. Given the antioxidative effect of molecular hydrogen, some recent studies suggest the potential use of molecular hydrogen as a biomedicine for the treatment of ARDS. In this study, we aimed to explore the protective effects of magnesium hydride (MgH

Indexed as

NF-kappa BRespiratory Distress SyndromeAnimalsApoptosisEndotoxinsHydrogenInflammationLipopolysaccharidesMagnesiumMiceNLR Family, Pyrin Domain-Containing 3 ProteinOxidative StressProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesEndotoxinsHydrogenLipopolysaccharidesMagnesiumNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinases

Identifiers

PMID35528515
PMCPMC9072031
OpenAlexW4224989641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.