Evidence map›Paper›PMID 35528508›Full record

ArticleOxidative medicine and cellular longevity2022

Interleukin 10 Attenuates Angiotensin II-Induced Aortic Remodelling by Inhibiting Oxidative Stress-Induced Activation of the Vascular p38 and NF-

Ming Qiu, Huanyu Shu, Lu Li, Yejiao Shen, Yunfan Tian, Yue Ji, Wei Sun, Yan Lu, Xiangqing Kong

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Neuroprotective effects of interleukin 10 in spinal cord injury.Frontiers in molecular neuroscience · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ming QiuSchool of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0002-6283-9659
Huanyu ShuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0003-1796-5637
Lu LiDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0002-7191-3849
Yejiao ShenDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0003-2997-9569
Yunfan TianDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0002-8111-2455
Yue JiDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0003-2464-8592
Wei SunDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0003-0833-0445
Yan LuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.ORCID https://orcid.org/0000-0003-3546-2849
Xiangqing KongSchool of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0003-3309-1140
Jiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin 10 (IL-10) is a probable anti-inflammatory factor that can attenuate hypertrophic remodelling caused by overloaded pressure and improve cardiac function. In this study, IL-10 was decreased in both the plasma of hypertensive patients and the aortic vessels of angiotensin II (Ang II)-induced hypertensive mice. IL-10 was unable to alter blood pressure in the case of Ang II-induced hypertension. The aortic thickness, collagen deposition, and the levels of fibrosis-associated markers, including collagen type I

Indexed as

Angiotensin IIHypertensionAnimalsCells, CulturedFibrosisHumansInterleukin-10Matrix Metalloproteinase 2MiceNF-kappa BOxidative Stressp38 Mitogen-Activated Protein KinasesSignal TransductionAngiotensin IIInterleukin-10Matrix Metalloproteinase 2NF-kappa Bp38 Mitogen-Activated Protein Kinases

Identifiers

PMID35528508
PMCPMC9072025
OpenAlexW4224936676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.