Evidence map›Paper›PMID 35528420›Full record

ArticleRSC advances2019

Erythrocyte membrane affinity chromatography, solid-phase extraction and UPLC-QTOF-MS/MS to screen active ingredients of Buyang Huanwu decoction.

Aiming Yu, Huazhu Zheng, Xiangli Yan, Shengxin Wang, Xiao Shen, Haozhen Zheng, Yingjiao Meng, Lisheng Wang

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aiming YuSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.ORCID https://orcid.org/0000-0003-2058-4448
Huazhu ZhengSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.
Xiangli YanSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.
Shengxin WangSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.
Xiao ShenSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.
Haozhen ZhengSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.
Yingjiao MengSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.
Lisheng WangSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine No. 232, Waihuan East Road, Panyu District Guangzhou 510006 China wlis68@126.com.ORCID https://orcid.org/0000-0001-8729-0423
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buyang Huanwu decoction (BHD) is a well-known traditional Chinese medicine that has long been used to treat ischemic brain damage which is associated with hemorheology. To screen active ingredients in BHD responsible for reducing blood viscosity by reducing red blood cell (RBC) lesions to treat ischemic stroke, a method involving RBC membrane binding and solid-phase extraction (SPE) was developed in this study. The components of BHD interacting with RBC were analyzed by mass spectrometry and four compounds, calycosin, paeoniflorin, 6-hydroxy behenol-3,6-di-

Identifiers

PMID35528420
PMCPMC9071827
OpenAlexW2973492755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.