Evidence map›Paper›PMID 35528325›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering

Oral Cavity Anatomical Site Image Classification and Analysis.

Zhiyun Xue, Paul C Pearlman, Kelly Yu, Anabik Pal, Tseng-Cheng Chen, Chun-Hung Hua, Chung Jan Kang, Chih-Yen Chien, Ming-Hsui Tsai, Cheng-Ping Wang and 2 more

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Weakly Supervised Learning of Oral Cavity Images for Separating Precancer from Cancer.IEEE International Conference on Omni-layer Intelligent Systems : COINS. IEEE International Conference on Omni-layer Intelligent Systems · 2026
    Article
  2. Oral Cancer Detection By Using Tabular Data Synthesis and Classification.Proceedings ... ICDM workshops. IEEE International Conference on Data Mining · 2025
    Article
  3. Detecting Oral Cancer Using Tabular Deep Learning.IEEE International Conference on Omni-layer Intelligent Systems : COINS. IEEE International Conference on Omni-layer Intelligent Systems · 2025
    Article
  4. Article
  5. Extraction of Ruler Markings For Estimating Physical Size of Oral Lesions.Proceedings of the ... IAPR International Conference on Pattern Recognition. International Conference on Pattern Recognition · 2022
    Article
  6. Automatic Detection of Oral Lesion Measurement Ruler Toward Computer-Aided Image-Based Oral Cancer Screening.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhiyun XueLister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894.
Paul C PearlmanCenter for Global Health, National Cancer Institute, National Institutes of Health, Rockville, MD 20850.
Kelly YuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20850.
Anabik PalLister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894.
Tseng-Cheng ChenNational Taiwan University Hospital, Taipei, Taiwan.
Chun-Hung HuaChina Medical University Hospital, Taichung, Taiwan.
Chung Jan KangChang Gung Memorial Hospital, Linkou, Taiwan.
Chih-Yen ChienChang Gung Memorial Hospital, Kaohsiung, Taiwan.
Ming-Hsui TsaiChina Medical University Hospital, Taichung, Taiwan.
Cheng-Ping WangNational Taiwan University Hospital, Taipei, Taiwan.
Anil K ChaturvediDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20850.
Sameer AntaniLister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894.

Funding

Machine learning and artificial intelligence research for clinical medical image processingZIALM010018 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ANTANI, SAMEER · 2021 to 2025
$9.0M
Intramural NIH HHS ZIA LM010018
6 · The paper itself

Abstract

Oral cavity cancer is a common cancer that can result in breathing, swallowing, drinking, eating problems as well as speech impairment, and there is high mortality for the advanced stage. Its diagnosis is confirmed through histopathology. It is of critical importance to determine the need for biopsy and identify the correct location. Deep learning has demonstrated great promise/success in several image-based medical screening/diagnostic applications. However, automated visual evaluation of oral cavity lesions has received limited attention in the literature. Since the disease can occur in different parts of the oral cavity, a first step is to identify the images of different anatomical sites. We automatically generate labels for six sites which will help in lesion detection in a subsequent analytical module. We apply a recently proposed network called ResNeSt that incorporates channel-wise attention with multi-path representation and demonstrate high performance on the test set. The average F1-score for all classes and accuracy are both 0.96. Moreover, we provide a detailed discussion on class activation maps obtained from both correct and incorrect predictions to analyze algorithm behavior. The highlighted regions in the class activation maps generally correlate considerably well with the region of interest perceived and expected by expert human observers. The insights and knowledge gained from the analysis are helpful in not only algorithm improvement, but also aiding the development of the other key components in the process of computer assisted oral cancer screening.

Indexed as

Deep LearningImage ClassificationLocation ClassificationOral Cancer

Identifiers

PMID35528325
PMCPMC9074925

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.