Evidence map›Paper›PMID 35528286›Full record

ReviewInternational journal of general medicine2022

Management of Postoperative Pain in Patients Following Spine Surgery: A Narrative Review.

Nitin K Prabhakar, Andrea L Chadwick, Chinwe Nwaneshiudu, Anuj Aggarwal, Vafi Salmasi, Theresa R Lii, Jennifer M Hah

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06869889 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Fluoroscopy-Guided Retrolaminar Block Versus Local Wound Infiltration for Post Lumbar Discectomy Analgesia: A Double-Blinded, Randomized Trial

TypeinterventionalSponsorZagazig UniversityRan2025 to 2026Enrolled130ConditionsAnalgesia, Disk Herniated Lumbar, Local InfiltrationArmsRetrolaminar plane block, Local wound infiltration
NCT06958718 phase4completednot on this mapstarted 2025, after this paper: background citation

Efficacy of Ultrasound-guided Versus Surgical Erector Spinae Plane Block With a Mixture of Bupivacaine and Dexmedetomidine in Lumbar Spinal Fusion Surgery: A Prospective Randomized Double-Blinded Clinical Trial.

TypeinterventionalSponsorFayoum University HospitalRan2025 to 2025Enrolled52ConditionsPost Operative PainArmsUltrasound Guided erector spinae plane block (UB), Surgical erector spinae plane block (SB), Dexmedetomidine, Bupivacaine Hcl 0.5% Inj
NCT06970704 nacompletednot on this mapstarted 2023, after this paper: background citation

Erector Spinae Plane Block Combined With General Anesthesia Versus General Anesthesia Alone in Spine Surgeries for Postoperative Pain, A Randomized Controlled Trial

TypeinterventionalSponsorAin Shams UniversityRan2023 to 2024Enrolled50ConditionsSpine Fusion, Spine Metastases, Postoperative PainArmsErector Spinae Plane Block using 0.25 % bupivacaine
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.

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  8. Acupuncture for postoperative rehabilitation in degenerative lumbar spinal diseases: mechanisms and clinical evidence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Nitin K PrabhakarDepartment of Orthopaedic Surgery, Stanford University, Stanford, CA, USA.
Andrea L ChadwickDepartment of Anesthesiology, Pain, and Perioperative Medicine, University of Kansas School of Medicine, Kansas City, KS, USA.
Chinwe NwaneshiuduDepartment of Anesthesiology, Perioperative and Pain Management, Mount Sinai Hospital, Icahn School of Medicine, New York, NY, USA.
Anuj AggarwalDepartment of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA, USA.
Vafi SalmasiDepartment of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA, USA.
Theresa R LiiDepartment of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA, USA.
Jennifer M HahDepartment of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9739-3968
Stanford Medicine · USMount Sinai Hospital · USStanford University · USUniversity of Kansas · US

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
NIDA NIH HHS T32 DA035165
6 · The paper itself

Abstract

Perioperative pain management is a unique challenge in patients undergoing spine surgery due to the increased incidence of both pre-existing chronic pain conditions and chronic postsurgical pain. Peri-operative planning and counseling in spine surgery should involve an interdisciplinary approach that includes consideration of patient-level risk factors, as well as pharmacologic and non-pharmacologic pain management techniques. Consideration of psychological factors and patient focused education as an adjunct to these measures is paramount in developing a personalized perioperative pain management plan. Understanding the currently available body of knowledge surrounding perioperative opioid management, management of opioid use disorder, regional/neuraxial anesthetic techniques, ketamine/lidocaine infusions, non-opioid oral analgesics, and behavioral interventions can be useful in developing a comprehensive, multi-modal treatment plan among patients undergoing spine surgery. Although many of these techniques have proved efficacious in the immediate postoperative period, long-term follow-up is needed to define the impact of such approaches on persistent pain and opioid use. Future techniques involving the use of precision medicine may help identify phenotypic and physiologic characteristics that can identify patients that are most at risk of developing persistent postoperative pain after spine surgery.

Indexed as

ketaminelidocaineopioid sparingpostoperative painregional anesthesiaspinesurgery

Identifiers

PMID35528286
PMCPMC9075013
OpenAlexW4225291136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.