Evidence map›Paper›PMID 35528212›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Multiscale Contrasts Between the Right and Left Ventricle Biomechanics in Healthy Adult Sheep and Translational Implications.

Wenqiang Liu, Michael Nguyen-Truong, Kristen LeBar, Kevin M Labus, Elisabeth Gray, Matt Ahern, Sunder Neelakantan, Reza Avazmohammadi, Kirk C McGilvray, Christian M Puttlitz and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Passive biaxial mechanical properties of sheep myocardium.Frontiers in bioengineering and biotechnology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Wenqiang LiuCardiovascular Biomechanics Laboratory, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States.
Michael Nguyen-TruongCardiovascular Biomechanics Laboratory, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States.
Kristen LeBarCardiovascular Biomechanics Laboratory, Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States.
Kevin M LabusOrthopaedic Bioengineering Research Laboratory, Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States.
Elisabeth GrayCardiovascular Biomechanics Laboratory, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States.
Matt AhernCardiovascular Biomechanics Laboratory, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States.
Sunder NeelakantanComputation Cardiovascular Bioengineering Lab, Department of Biomedical Engineering, Texas A&M University, College Station, TX, United States.
Reza AvazmohammadiComputation Cardiovascular Bioengineering Lab, Department of Biomedical Engineering, Texas A&M University, College Station, TX, United States.
Kirk C McGilvrayOrthopaedic Bioengineering Research Laboratory, Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States.
Christian M PuttlitzOrthopaedic Bioengineering Research Laboratory, Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States.
Zhijie WangCardiovascular Biomechanics Laboratory, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States.
Colorado State University · USTexas A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac biomechanics play a significant role in the progression of structural heart diseases (SHDs). SHDs alter baseline myocardial biomechanics leading to single or bi-ventricular dysfunction. But therapies for left ventricle (LV) failure patients do not always work well for right ventricle (RV) failure patients. This is partly because the basic knowledge of baseline contrasts between the RV and LV biomechanics remains elusive with limited discrepant findings. The aim of the study was to investigate the multiscale contrasts between LV and RV biomechanics in large animal species. We hypothesize that the adult healthy LV and RV have distinct passive anisotropic biomechanical properties.

Indexed as

anisotropycollagen isoformFung exponential strain energy functionovinestructurally informed model

Identifiers

PMID35528212
PMCPMC9068898
OpenAlexW4224298219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.