Evidence map›Paper›PMID 35528186›Full record

ArticleInfection and drug resistance2022

Minocycline Susceptibility and

Jia-Ling Yang, Chia-Jui Yang, Yu-Chung Chuang, Wang-Huei Sheng, Yee-Chun Chen, Shan-Chwen Chang

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Multidrug-ResistantInfection and drug resistance · 2025
    Article
  6. The challenges of difficult-to-treatClinical microbiology reviews · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jia-Ling YangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
Chia-Jui YangDepartment of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Yu-Chung ChuangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.ORCID 0000-0003-3094-8276
Wang-Huei ShengDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
Yee-Chun ChenDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.ORCID 0000-0002-1816-9010
Shan-Chwen ChangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
National Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: In this study, we evaluated the minocycline susceptibility rate in carbapenem-resistant Patients and Methods: A total of 100 genetically unrelated CRAB clinical strains from bloodstream infection were randomly collected from a medical center in Taiwan. An argument for a new minocycline susceptibility breakpoint of 1 mg/L was suggested based on pharmacokinetic (PK) and pharmacodynamic (PD) studies. Strains with minocycline minimum inhibitory concentrations (MICs) of >1 mg/L were classified as PK-PD non-susceptible. Results: Fifty-five (55%) CRAB strains were susceptible to minocycline according to the Clinical and Laboratory Standards Institute (CLSI) criteria, among which 98.2% (54/55) were PK-PD non-susceptible. The minocycline MIC Conclusion: At our institute, most CRAB strains were PK-PD non-susceptible and most carried

Indexed as

CRABeffluxminocycline PK-PD non-susceptibilitymultidrug resistance

Identifiers

PMID35528186
PMCPMC9075780
OpenAlexW4225266769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.