Evidence map›Paper›PMID 35528151›Full record

ArticleActa clinica Croatica2021

CROATIAN GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF NONALCOHOLIC FATTY LIVER DISEASE.

Lucija Virović Jukić, Ivica Grgurević, Ivana Mikolašević, Tajana Filipec Kanižaj, Sandra Milić, Anna Mrzljak, Marina Premužić, Irena Hrstić, Ivana Knežević-Štromar, Neven Ljubičić and 11 more

Open access · diamondAbstract read
In one paragraph

Article in Acta clinica Croatica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Lucija Virović JukićSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Ivica GrgurevićSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Ivana MikolaševićCroatian Society of Gastroenterology, Zagreb, Croatia.
Tajana Filipec KanižajSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Sandra MilićCroatian Society of Gastroenterology, Zagreb, Croatia.
Anna MrzljakSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Marina PremužićCroatian Society of Gastroenterology, Zagreb, Croatia.
Irena HrstićCroatian Society of Gastroenterology, Zagreb, Croatia.
Ivana Knežević-ŠtromarCroatian Society of Gastroenterology, Zagreb, Croatia.
Neven LjubičićSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Rajko OstojićSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Sanja Stojsavljević ShapeskiSestre milosrdnice University Hospital Center, Zagreb, Croatia.
Vjekoslava Amerl-ŠakićVjekoslava Amerl-Šakić Family Medicine Practice, Zagreb, Croatia.
Nina Bašić MarkovićSchool of Medicine, University of Rijeka, Rijeka, Croatia.
Marko RađaHealthcare Center of the Split-Dalmatia County, Split, Croatia.
Dragan SoldoSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Nikola SobočanSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Miloš LalovacCroatian Society of Gastroenterology, Zagreb, Croatia.
Željko PuljizCroatian Society of Gastroenterology, Zagreb, Croatia.
Kristian PodrugCroatian Society of Gastroenterology, Zagreb, Croatia.
Dinko LadićCroatian Society of Gastroenterology, Zagreb, Croatia.
Sisters of Charity Hospital · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a term describing excessive accumulation of fat in hepatocytes, and is associated with metabolic syndrome and insulin resistance. NAFLD prevalence is on increase and goes in parallel with the increasing prevalence of metabolic syndrome and its components. That is why Croatian guidelines have been developed, which cover the screening protocol for patients with NAFLD risk factors, and the recommended diagnostic work-up and treatment of NAFLD patients. NAFLD screening should be done in patients with type 2 diabetes mellitus, or persons with two or more risk factors as part of metabolic screening, and is carried out by noninvasive laboratory and imaging methods used to detect fibrosis. Patient work-up should exclude the existence of other causes of liver injury and determine the stage of fibrosis as the most important factor in disease prognosis. Patients with initial stages of fibrosis continue to be monitored at the primary healthcare level with the management of metabolic risk factors, dietary measures, and increased physical activity. Patients with advanced fibrosis should be referred to a gastroenterologist/hepatologist for further treatment, monitoring, and detection and management of complications.

Indexed as

Diabetes Mellitus, Type 2Metabolic SyndromeNon-alcoholic Fatty Liver DiseaseCroatiaFibrosisHumansLiver CirrhosisCirrhosisDiagnosticsFibrosisHepatocellular carcinomaMetabolic syndromeNonalcoholic fatty liver disease (NAFLD)Nonalcoholic steatohepatitis (NASH)Noninvasive methodsScreeningTreatment

Identifiers

PMID35528151
PMCPMC9036273
OpenAlexW3185323321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.