Evidence map›Paper›PMID 35528138›Full record

ArticleJournal of global optimization : an international journal dealing with theoretical and computational aspects of seeking global optima and their applications in science, management and engineering2022

NMR Assignment through Linear Programming.

José F S Bravo-Ferreira, David Cowburn, Yuehaw Khoo, Amit Singer

Abstract read
In one paragraph

Article in Journal of global optimization : an international journal dealing with theoretical and computational aspects of seeking global optima and their applications in science, management and engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

José F S Bravo-FerreiraPACM, Princeton University, NJ 08540.
David CowburnDepartments of Biochemistry and of Physiology and Biophysics, Albert Einstein College of Medicine, NY 10461.
Yuehaw KhooDepartment of Statistics, University of Chicago, IL 60637.
Amit SingerDepartment of Mathematics and PACM, Princeton University, NJ 08540.

Funding

The dynamic mechanism of nuclear transport visualized at the atomic scaleR01GM117212 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI COWBURN, DAVID · 2016 to 2023
$3.7M
Reconstruction of heterogeneous and small macromolecules by cyro-EMR01GM136780 · NIGMS · PRINCETON UNIVERSITY · PI SINGER, AMIT · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM117212NIGMS NIH HHS R01 GM136780
6 · The paper itself

Abstract

Nuclear Magnetic Resonance (NMR) Spectroscopy is the second most used technique (after X-ray crystallography) for structural determination of proteins. A computational challenge in this technique involves solving a discrete optimization problem that assigns the resonance frequency to each atom in the protein. This paper introduces LIAN (LInear programming Assignment for NMR), a novel linear programming formulation of the problem which yields state-of-the-art results in simulated and experimental datasets.

Indexed as

Linear programming relaxationNMR spectroscopyResonance assignment problemShortest path problem

Identifiers

PMID35528138
PMCPMC9070988

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.