Evidence map›Paper›PMID 35527995›Full record

Observational studyFrontiers in endocrinology2022

Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study.

Marília B Gomes, Fengming Tang, Hungta Chen, Javier Cid-Ruzafa, Peter Fenici, Kamlesh Khunti, Wolfgang Rathmann, Marina V Shestakova, Filip Surmont, Hirotaka Watada and 5 more

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marília B GomesDepartment of Medicine, Diabetes Unit, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Fengming TangSaint Luke's Mid America Heart Institute, Kansas City, MO, United States.
Hungta ChenMedical/Payer Evidence Statistics, BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, MD, United States.
Javier Cid-RuzafaEvidera, Barcelona, Spain.
Peter FeniciBioPharmaceuticals Medical, AstraZeneca, Cambridge, United Kingdom.
Kamlesh KhuntiPrimary Care Diabetes and Vascular Medicine, University of Leicester, Leicester, United Kingdom.
Wolfgang RathmannInstitute for Biometrics and Epidemiology, German Diabetes Centre, Düsseldorf, Germany.
Marina V ShestakovaEndocrinology Research Centre, Diabetes Institute, Moscow, Russia.
Filip SurmontBioPharmaceuticals Medical, AstraZeneca, Luton, United Kingdom.
Hirotaka WatadaGraduate School of Medicine, Juntendo University, Tokyo, Japan.
Jesús MedinaBioPharmaceuticals Medical, AstraZeneca, Madrid, Spain.
Iichiro ShimomuraGraduate School of Medicine, Osaka University, Osaka, Japan.
Gabriela Luporini SaraivaMedical/Payer Evidence Statistics, BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, MD, United States.
Andrew CooperBioPharmaceuticals Medical, AstraZeneca, Cambridge, United Kingdom.
Antonio NicolucciCentre for Outcomes Research and Clinical Epidemiology, Pescara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DISCOVER is a 3-year observational study program of 15,983 people with type 2 diabetes initiating second-line glucose-lowering therapy in 38 countries. We investigated the association between socioeconomic status and both the availability of a baseline glycated hemoglobin (HbA1c) measurement and poor glycemic control (HbA1c level ≥ 9.0%) in participants enrolled in DISCOVER. Factors associated with a lack of baseline HbA1c measurement or an HbA1c level ≥ 9.0% were assessed using three-level hierarchical logistic models. Overall, 19.1% of participants did not have a baseline HbA1c measurement recorded. Lower-middle country income (vs. high) and primary/no formal education (vs. university education) were independently associated with a reduced likelihood of having a baseline HbA1c measurement (odds ratio [95% confidence interval]: 0.11 [0.03-0.49] and 0.81 [0.66-0.98], respectively. Of the participants with an available HbA1c measurement, 26.9% had an HbA1c level ≥ 9.0%; 68.7% of these individuals were from lower- or upper-middle-income countries. Factors associated with an increased likelihood of poor glycemic control included low country income, treatment at a site with public and/or governmental funding (vs. private funding) and having public or no health insurance (vs. private). A substantial proportion of DISCOVER participants did not have an HbA1c measurement; more than one-quarter of these participants had poorly controlled type 2 diabetes. Both individual- and country-level socioeconomic factors are associated with the quality of care regarding glycemic control. Awareness of these factors could help improve the management of patients with type 2 diabetes.

Indexed as

Diabetes Mellitus, Type 2Blood GlucoseGlycated HemoglobinGlycemic ControlHumansSocioeconomic FactorsBlood GlucoseGlycated Hemoglobinglucose-lowering drugglycemic controlobservational studysocioeconomic factorstype 2 diabetes

Identifiers

PMID35527995
PMCPMC9072655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.