Evidence map›Paper›PMID 35527993›Full record

ArticleFrontiers in endocrinology2022

Radiomic Model for Determining the Value of Elasticity and Grayscale Ultrasound Diagnoses for Predicting BRAF

Yu-Guo Wang, Fei-Ju Xu, Enock Adjei Agyekum, Hong Xiang, Yuan-Dong Wang, Jin Zhang, Hui Sun, Guo-Liang Zhang, Xiang-Shu Bo, Wen-Zhi Lv and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. EnhancingQuantitative imaging in medicine and surgery · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Research on ultrasound-based radiomics: a bibliometric analysis.Quantitative imaging in medicine and surgery · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. A Review of the Role of Ultrasound Radiomics and Its Application and Limitations in the Investigation of Thyroid Disease.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Yu-Guo WangDepartment of Ultrasound, Jiangsu Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing, China.
Fei-Ju XuDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Enock Adjei AgyekumDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Hong XiangDepartment of Pediatrics, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Yuan-Dong WangDepartment of Radiotherapy, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Jin ZhangDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Hui SunDepartment of Pathology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Guo-Liang ZhangDepartment of General Surgery, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Xiang-Shu BoDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Wen-Zhi LvDepartment of Artificial Intelligence, Julei Technology, Company, Wuhan, China.
Xian WangDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Shu-Dong HuDepartment of Radiology, Affiliated Hospital of Jiangnan University, Wuxi, China.
Xiao-Qin QianDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Jiangsu University · CNAffiliated Hospital of Jiangsu University · CNWuxi Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRAF Methods: 138 patients with PTC who underwent preoperative ultrasound between January 2014 and 2021 were retrospectively examined. Patients were divided into BRAF Results: Eight radiomics features were extracted from the grayscale ultrasonogram, and five radiomics features were extracted from the elasticity ultrasonogram. Three models were developed using these radiomic features. The models were derived from elasticity ultrasound, grayscale ultrasound, and a combination of grayscale and elasticity ultrasound, with areas under the curve (AUC) 0.952 [95% confidence interval (CI), 0.914-0.990], AUC 0.792 [95% CI, 0.703-0.882], and AUC 0.985 [95% CI, 0.965-1.000] in the training dataset, AUC 0.931 [95% CI, 0.841-1.000], AUC 0. 725 [95% CI, 0.569-0.880], and AUC 0.938 [95% CI, 0.851-1.000] in the test dataset, respectively. Conclusion: The radiomic model based on grayscale and elasticity ultrasound had a good predictive value for BRAF

Indexed as

Proto-Oncogene Proteins B-rafThyroid NeoplasmsElasticityHumansMutationRetrospective StudiesThyroid Cancer, PapillaryUltrasonographyBRAF protein, humanProto-Oncogene Proteins B-rafBRAF-V600Emodelpapillary thyroid carcinomaradiomicultrasonic examination

Identifiers

PMID35527993
PMCPMC9074386
OpenAlexW4224282958

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.