Evidence map›Paper›PMID 35527918›Full record

ArticleACS applied nano materials2019

Clusters of Nanoscale Liposomes Modulate the Release of Encapsulated Species and Mimic the Compartmentalization Intrinsic in Cell Structures.

Igor Kevin Mkam Tsengam, Marzhana Omarova, Lauren Shepherd, Nicholas Sandoval, Jibao He, Elizabeth Kelley, Vijay John

Abstract read
In one paragraph

Article in ACS applied nano materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Igor Kevin Mkam TsengamDepartment of Chemical & Biomolecular Engineering, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, United States.ORCID 0000-0002-6587-0555
Marzhana OmarovaDepartment of Chemical & Biomolecular Engineering, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, United States.
Lauren ShepherdDepartment of Chemical & Biomolecular Engineering, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, United States.ORCID 0000-0001-6720-5439
Nicholas SandovalDepartment of Chemical & Biomolecular Engineering, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, United States.ORCID 0000-0002-1743-3975
Jibao HeCoordinated Instrumentation Facility, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, United States.
Elizabeth KelleyCenter for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.ORCID 0000-0002-6128-8517
Vijay JohnDepartment of Chemical & Biomolecular Engineering, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, United States.ORCID 0000-0001-5426-7585

Funding

Intramural NIST DOC 9999-NIST
6 · The paper itself

Abstract

We report the ability to place a high concentration of liposomes in a confined volume as a multicompartment cluster that mimics biological cells and allows for the modulation of release of encapsulated species. The formation of these coated multicompartmental structures is achieved by first binding liposomes into clusters before encapsulating them within a two-dimensional metal-organic framework composed of tannic acid coordinated with a metal ion. The essential feature is a molecularly thin skin over a ssystem of clustered liposomes in a pouch. The structural features of these pouches are revealed by small-angle scattering and electron microscopy. Through cryogenic electron microscopy, clusters with intact liposomes are observed that appear to be encapsulated within a pouch. Small-angle X-ray scattering shows the emergence of a relatively weak Bragg peak at

Indexed as

cell mimicsdrug deliveryFRETliposomesmetal–phenolic network

Identifiers

PMID35527918
PMCPMC9074808

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.