Evidence map›Paper›PMID 35527869›Full record

ReviewRSC advances2019

Metal nanoparticles fabricated by green chemistry using natural extracts: biosynthesis, mechanisms, and applications.

Hesham R El-Seedi, Rehan M El-Shabasy, Shaden A M Khalifa, Aamer Saeed, Afzal Shah, Raza Shah, Faiza Jan Iftikhar, Mohamed M Abdel-Daim, Abdelfatteh Omri, Nahid H Hajrahand and 5 more

Abstract readReview
In one paragraph

Review in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Metallo-herb complexes as emerging therapeutics: chemistry, synthesis approaches, and pharmacological insights.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  13. Review
  14. Review
  15. Green Synthesis of Copper Oxide Nanoparticles UsingNanomaterials (Basel, Switzerland) · 2026
    Article
  16. Article
  17. Ni-Fe Nanoparticles fromCurrent pharmaceutical design · 2026
    Article
  18. Review
  19. Review
  20. Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hesham R El-SeediPharmacognosy Group, Department of Medicinal Chemistry, Uppsala University, Biomedical Centre Box 574 SE-751 23 Uppsala Sweden hesham.el-seedi@ilk.uu.se +46 18 4714207.ORCID https://orcid.org/0000-0002-2519-6690
Rehan M El-ShabasyDepartment of Chemistry, Faculty of Science, Menoufia University Egypt.
Shaden A M KhalifaClinical Research Centre, Karolinska University Hospital Huddinge Sweden.
Aamer SaeedDepartment of Chemistry, Quaid-i-Azam University 45320 Islamabad Pakistan.
Afzal ShahDepartment of Chemistry, College of Science, University of Bahrain Sakhir 32038 Bahrain.ORCID https://orcid.org/0000-0002-6037-1087
Raza ShahH.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi Karachi-75270 Pakistan.
Faiza Jan IftikharDepartment of Chemistry, Quaid-i-Azam University 45320 Islamabad Pakistan.
Mohamed M Abdel-DaimPharmacology Department, Faculty of Veterinary Medicine, Suez Canal University Ismailia 41522 Egypt.ORCID https://orcid.org/0000-0002-4341-2713
Abdelfatteh OmriCenter of Excellence in Bionoscience Research, King Abdulaziz University (KAU) Jeddah 21589 Saudi Arabia.
Nahid H HajrahandCenter of Excellence in Bionoscience Research, King Abdulaziz University (KAU) Jeddah 21589 Saudi Arabia.
Jamal S M SabirCenter of Excellence in Bionoscience Research, King Abdulaziz University (KAU) Jeddah 21589 Saudi Arabia.
Xiaobo ZouCollege of Food and Biological Engineering, Jiangsu University Zhenjiang 212013 China.ORCID https://orcid.org/0000-0001-5719-7025
Mohammed F HalabiAl-Rayan Research and Innovation Center, Al-Rayan Colleges Medina 42541 Saudi Arabia.
Wessam SarhanZewail City for Science and Technology Cairo Egypt.
Weisheng GuoTranslational Medicine Center, The Second Affiliated Hospital, Guangzhou Medical University Guangzhou 510260 China tjuguoweisheng@126.com +86-020-34153830.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles (NPs) are new inspiring clinical targets that have emerged from persistent efforts with unique properties and diverse applications. However, the main methods currently utilized in their production are not environmentally friendly. With the aim of promoting a green approach for the synthesis of NPs, this review describes eco-friendly methods for the preparation of biogenic NPs and the known mechanisms for their biosynthesis. Natural plant extracts contain many different secondary metabolites and biomolecules, including flavonoids, alkaloids, terpenoids, phenolic compounds and enzymes. Secondary metabolites can enable the reduction of metal ions to NPs in eco-friendly one-step synthetic processes. Moreover, the green synthesis of NPs using plant extracts often obviates the need for stabilizing and capping agents and yields biologically active shape- and size-dependent products. Herein, we review the formation of metallic NPs induced by natural extracts and list the plant extracts used in the synthesis of NPs. In addition, the use of bacterial and fungal extracts in the synthesis of NPs is highlighted, and the parameters that influence the rate of particle production, size, and morphology are discussed. Finally, the importance and uniqueness of NP-based products are illustrated, and their commercial applications in various fields are briefly featured.

Identifiers

PMID35527869
PMCPMC9069627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.