Evidence map›Paper›PMID 35527706›Full record

ArticleHepatology communications2022

Nonalcoholic fatty liver disease prevalence and severity in Asian Americans from the national health and nutrition examination surveys 2017-2018.

Emily Truong, Yee Hui Yeo, Galen Cook-Wiens, Mark Muthiah, Ju Dong Yang, Vinay Sundaram, Devon Chang, Tsuyoshi Todo, Irene K Kim, Shelly C Lu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Emily TruongDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-9167-3299
Yee Hui YeoDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Galen Cook-WiensCedars-Sinai Medical Center, Los Angeles, California, USA.
Mark MuthiahNational University of Singapore, Singapore.
Ju Dong YangKarsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0001-7834-9825
Vinay SundaramKarsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-1450-7756
Devon ChangArnold O. Beckman High School, Irvine, California, USA.
Tsuyoshi TodoComprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, California, USA.
Irene K KimComprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, California, USA.
Shelly C LuKarsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Veronica Wendy SetiawanUSC Research Center for Liver Diseases, University of Southern California School of Medicine, Los Angeles, California, USA.
Vincent W S WongThe Chinese University of Hong Kong, Hong Kong.ORCID 0000-0003-2215-9410
Stephen A HarrisonRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Naim AlkhouriArizona Liver Health, Phoenix, Arizona, USA.
Mazen NoureddinKarsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Cedars-Sinai Medical Center · USArizona Liver Health · USArnold and Mabel Beckman Foundation · USChinese University of Hong Kong · HKJohn Radcliffe Hospital · GBNational University of Singapore · SGUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have examined nonalcoholic fatty liver disease (NAFLD) prevalence and severity in Asians; however, this is not well understood in Asian Americans (both East and South Asian Americans) as few studies have analyzed this population. We aimed to describe characteristics, prevalence of NAFLD, and its severity in Asian Americans in the National Health and Nutrition Examination Surveys (NHANES) from 2017 to 2018. Respondents 18 years and older with interview, laboratory testing, and transient elastography data were included. Other causes of liver disease were excluded. Controlled attenuation parameter (CAP) cutoff ≥ 274 dB/m, as published in the literature, defined NAFLD. Sensitivity analysis for CAP cutoffs ≥ 248 and ≥302 dB/m were performed. We found that 450 out of 3639 respondents were Asian Americans, and prevalence using CAP ≥ 274 dB/m was 43.23%. Using sensitivity analysis cutoffs of CAP ≥ 248 dB/m and CAP ≥ 302 dB/m, the prevalence was 57.38% and 28.03%, respectively. Compared with non-Asian Americans with NAFLD, Asian Americans with NAFLD had significantly lower body mass index (BMI) and less prevalent smoking history. Comorbidities, such as prediabetes, diabetes, and hypertension, were not significantly different between Asian and non-Asian Americans with NAFLD. Compared to non-Asian Americans with NAFLD, Asian Americans with NAFLD exhibited higher aminotransferases and triglycerides. Fibrosis assessed by transient elastography was not significantly different between Asian and non-Asian Americans with NAFLD. Despite decreased prevalence of BMI ≥ 30 kg/m

Indexed as

Elasticity Imaging TechniquesNon-alcoholic Fatty Liver DiseaseFibrosisHumansNutrition SurveysPrevalenceUnited States

Identifiers

PMID35527706
PMCPMC9426392
OpenAlexW4229375880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.