ArticleJournal of Parkinson's disease2022
Independent and Joint Associations of Tea Consumption and Smoking with Parkinson's Disease Risk in Chinese Adults.
Article in Journal of Parkinson's disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Lifestyle medicine for neuroprotection: evidence and implementation in Asian contexts.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Exercise and smoking: health rivals revealing shared protective mechanisms in Parkinson's?NPJ Parkinson's disease · 2026Review
- Smoking and the risk of neurodegenerative diseases in a Chinese case-control study.BMJ neurology open · 2026Article
- Habitual sweet and bitter beverage consumption in relation to the risk of frailty and sarcopenia-related traits: a Mendelian randomization study.BMC geriatrics · 2025Article
- A Genome-wide study on the genetic and causal effects of smoking in neurodegeneration.Journal of translational medicine · 2025Article
- Factors associated with phenoconversion of idiopathic rapid eye movement sleep behavior disorder: a prospective study.NPJ Parkinson's disease · 2025Article
- Inhibitory Role of L-theanine, a Structural Analogue of Glutamate, against GluR5 Kainate Receptor and its Prospective Utility against Excitotoxicity.Central nervous system agents in medicinal chemistry · 2024Article
- Age at smoking initiation and smoking cessation influence the incidence of stroke in China: a 10-year follow-up study.Journal of thrombosis and thrombolysis · 2023Article
- The Association between Coffee and Tea Consumption at Midlife and Risk of Dementia Later in Life: The HUNT Study.Nutrients · 2023Article
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Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundExisting limited evidence suggests that smoking and tea consumption may be associated with a lower risk of Parkinson's disease (PD). However, less is known about the independent and joint roles of these two habits, which are often clustered among Chinese, on PD risk.
objectiveTo prospectively examine the independent and joint association of tea consumption and smoking with the risk of PD.
methodsThe China Kadoorie Biobank (CKB) study recruited 512,725 participants aged 30 to 79 years from ten areas across China since 2004. Information on smoking and tea consumption was collected at baseline, and PD cases were ascertained by linkage to the national health insurance system and death registry. Cox proportional hazards models were used to estimate the multivariable-adjusted hazard ratios (HRs) and corresponding 95%confidence intervals (CIs).
resultsDuring a median of 10.8 years of follow-up, 922 PD cases were recorded. Compared with participants who never consumed tea, the HR (95%CI) for daily consumers was 0.68 (0.55, 0.84). Compared with participants who never or occasionally smoked, the HR (95%CI) for current smokers was 0.66 (0.53, 0.82). Those who had a clustering habit of smoking and tea consumption had a 38%(HR = 0.62; 95%CI: 0.49, 0.79) lower PD risk than those who consumed none. However, there were no statistically significant multiplicative or additive interaction for tea consumption and smoking on PD risk.
conclusionWe found that smoking and daily tea consumption were independently inversely associated with the risk of PD.
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