Evidence map›Paper›PMID 35527300›Full record

SynthesisHealth and quality of life outcomes2022

Health related quality of life and its association with social support among people living with HIV/AIDS receiving antiretroviral therapy in Ethiopia: a systematic review and meta-analysis.

Nebiyu Mengistu, Habtamu Endashaw Hareru, Seid Shumye, Solomon Yimer, Daniel Sisay, Abdene Weya Kaso, Temesgen Muche, Chalachew Kassaw, Negasa Eshete Soboksa, Wondwosen Molla and 2 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Motivated by mortality:Exploratory research in clinical and social pharmacy · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Nebiyu MengistuDepartment of Psychiatry, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia. nebiyumen@gmail.com.ORCID http://orcid.org/0000-0003-1411-2591
Habtamu Endashaw HareruSchool of Public Health, College of Medicine and Health Science, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Seid ShumyeDepartment of Psychiatry, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Solomon YimerDepartment of Psychiatry, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Daniel SisaySchool of Public Health, College of Medicine and Health Science, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Abdene Weya KasoSchool of Public Health, College of Medicine and Health Science, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Temesgen MucheDepartment of Human Nutrition, College of Medicine and Health Science, Dilla University, Dilla, Ethiopia.
Chalachew KassawDepartment of Psychiatry, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Negasa Eshete SoboksaSchool of Public Health, College of Medicine and Health Science, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Wondwosen MollaDepartment of Midwifery, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Alemayehu MollaDepartment of Psychiatry, Dilla University, P.O. Box (DU): 419, Dilla, Ethiopia.
Bereket DukoCurtin School of Population Health, Curtin University, Perth, WA, Australia.
Dilla University · ETCurtin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople living with HIV/AIDS (PLWHA) are frequently confronted with severe social issues such as rejection, abandonment, criticism, and stigma. This would negatively affect their quality of life. Several studies have been conducted so far to assess factors affecting the health-related quality of life among people living with HIV/AIDS who are on antiretroviral therapy (ART) in Ethiopia. However, to our knowledge, there is no previous study that has summarized the results of the studies that investigated health-related quality of life (HRQOL) among PLWHA in Ethiopia. Therefore, the purpose of this review was to estimate the pooled prevalence of HRQOL and its association with social support among people living with HIV/AIDS (PLWHA) on ART in Ethiopia.

methodsA systematic search was carried out using several electronic databases (PubMed, Science Direct, Web of Science, and Cochrane electronic), Google Scholar, Google, and a manual search of the literature on health-related quality of life among people living with HIV/AIDS who are on ART. A Microsoft Excel data extraction sheet was used to extract pertinent data from an individual study. To assess the heterogeneity of primary articles, the Cochrane Q test statistics and the I2 test were carried out, and a random effects meta-analysis was used to estimate the pooled prevalence of HRQOL.

resultOut of the 493 articles reviewed, ten with a total of 3257 study participants were eligible for meta-analysis. The pooled prevalence of HRQOL among people living with HIV/AIDS who are on antiretroviral therapy in Ethiopia was 45.27%. We found that strong perceived social support was significantly associated with higher levels of subjectively perceived HRQOL. PLWHA who were on ART and had good social support were four times more likely to report higher HRQOL when compared to their counterparts [AOR = 4.01, 95% CI 3.07-5.23].

conclusionA substantial number of PLWHA had poor HRQOL in Ethiopia. Social support was significantly associated with HRQOL among people living with HIV/AIDS. Hence, it's recommended to encourage suitable intervention at every follow-up visit, and psycho-social support is also warranted to improve the quality of life.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsEthiopiaHumansQuality of LifeSocial SupportAntiretroviral therapyEthiopiaHIV/AIDSQuality of lifeSocial support

Identifiers

PMID35527300
PMCPMC9080185
OpenAlexW4229336333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.