Evidence map›Paper›PMID 35527283›Full record

ArticleGeroScience2022

CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice.

Sara López-Bellón, Sandra Rodríguez-López, José A González-Reyes, M Isabel Burón, Rafael de Cabo, José M Villalba

Open access · hybridAbstract read
In one paragraph

Article in GeroScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Cytochrome bAging cell · 2024
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sara López-BellónDepartamento de Biología Celular, Fisiología E Inmunología, Universidad de Córdoba, Campus de Rabanales, Edificio Severo Ochoa, 3ª planta, Campus de Excelencia Internacional Agroalimentario, ceiA3, 14014, Cordoba, Spain.ORCID 0000-0003-1978-3730
Sandra Rodríguez-LópezDepartamento de Biología Celular, Fisiología E Inmunología, Universidad de Córdoba, Campus de Rabanales, Edificio Severo Ochoa, 3ª planta, Campus de Excelencia Internacional Agroalimentario, ceiA3, 14014, Cordoba, Spain.ORCID 0000-0002-5088-6458
José A González-ReyesDepartamento de Biología Celular, Fisiología E Inmunología, Universidad de Córdoba, Campus de Rabanales, Edificio Severo Ochoa, 3ª planta, Campus de Excelencia Internacional Agroalimentario, ceiA3, 14014, Cordoba, Spain.ORCID 0000-0003-1918-5490
M Isabel BurónDepartamento de Biología Celular, Fisiología E Inmunología, Universidad de Córdoba, Campus de Rabanales, Edificio Severo Ochoa, 3ª planta, Campus de Excelencia Internacional Agroalimentario, ceiA3, 14014, Cordoba, Spain.ORCID 0000-0003-2923-2684
Rafael de CaboTranslational Gerontology Branch, National Institute On Aging, National Institutes of Health, Baltimore, MD, USA.ORCID 0000-0002-3354-2442
José M VillalbaDepartamento de Biología Celular, Fisiología E Inmunología, Universidad de Córdoba, Campus de Rabanales, Edificio Severo Ochoa, 3ª planta, Campus de Excelencia Internacional Agroalimentario, ceiA3, 14014, Cordoba, Spain. jmvillalba@uco.es.ORCID 0000-0001-8554-3802
University of Córdoba · ESNational Institutes of Health · US

Funding

NRF2 interactions with SIRT1 and its role on caloric restrictionZIAAG000361 · NIA · NATIONAL INSTITUTE ON AGING · PI DE CABO, RAFAEL · 2009 to 2024
$5.3M
Aging and CR effects on the Plasma Membrane Redox SystemZIAAG000362 · NIA · NATIONAL INSTITUTE ON AGING · PI DE CABO, RAFAEL · 2009 to 2025
$5.0M
6 · The paper itself

Abstract

Cytochrome b

Indexed as

MitochondriaMitochondria, MuscleAnimalsAutophagyMaleMiceMice, TransgenicMuscle, SkeletalAgingAutophagyCytochrome b 5 reductaseMitochondriaSkeletal muscle

Identifiers

PMID35527283
PMCPMC9616997
OpenAlexW4229363808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.