Evidence map›Paper›PMID 35526777›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

Practical Implementation of Genetics: New Concepts in Immunogenomics to Predict, Prevent, and Diagnose Drug Hypersensitivity.

Pooja Deshpande, Yueran Li, Michael Thorne, Amy M Palubinsky, Elizabeth J Phillips, Andrew Gibson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Pooja DeshpandeInstitute for Immunology and Infectious Disease, Murdoch University, Perth, Western Australia, Australia.
Yueran LiInstitute for Immunology and Infectious Disease, Murdoch University, Perth, Western Australia, Australia.
Michael ThorneInstitute for Immunology and Infectious Disease, Murdoch University, Perth, Western Australia, Australia.
Amy M PalubinskyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Elizabeth J PhillipsInstitute for Immunology and Infectious Disease, Murdoch University, Perth, Western Australia, Australia; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Andrew GibsonInstitute for Immunology and Infectious Disease, Murdoch University, Perth, Western Australia, Australia. Electronic address: a.gibson@iiid.murdoch.edu.au.
Murdoch University · AUVanderbilt University Medical Center · US

Funding

NATIENS: A Phase III Randomized Double Blinded Study to Determine the Mechanisms and Optimal Management of Stevens-Johnson Syndrome and Toxic Epidermal NecrolysisU01AI154659 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2020 to 2025
$15.5M
Understanding and preventing HLA-associated drug reactionsP50GM115305 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH, RODEN, DAN M · 2015 to 2019
$13.0M
Genetic risk and long-term outcomes associated with Drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in survivorsR01HG010863 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2019 to 2022
$3.1M
NHGRI NIH HHS R01 HG010863NIAID NIH HHS U01 AI154659NIGMS NIH HHS P50 GM115305
6 · The paper itself

Abstract

Delayed drug hypersensitivities are CD8

Indexed as

CD8-Positive T-LymphocytesDrug HypersensitivityHLA AntigensHumansReceptors, Antigen, T-CellHLA AntigensReceptors, Antigen, T-CellDrug hypersensitivityEndoplasmic reticulum aminopeptidaseHuman leukocyte antigenImmunogenomicsSingle-cell sequencingT cell receptor

Identifiers

PMID35526777
PMCPMC9948495
OpenAlexW4229058267

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.