Evidence map›Paper›PMID 35526172›Full record

ArticleEJNMMI physics2022

Monte Carlo modelling of a compact CZT-based gamma camera with application to

Daniel Roth, Erik Larsson, Michael Ljungberg, Katarina Sjögreen Gleisner

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Monte Carlo methods for medical imaging research.Biomedical engineering letters · 2024
    Review
  5. Feasibility ofEJNMMI physics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daniel RothMedical Radiation Physics, Lund, Lund University, Lund, Sweden. daniel.roth@med.lu.se.ORCID http://orcid.org/0000-0002-4128-0032
Erik LarssonDepartment of Radiation Physics, Skåne University Hospital, Lund, Sweden.
Michael LjungbergMedical Radiation Physics, Lund, Lund University, Lund, Sweden.
Katarina Sjögreen GleisnerMedical Radiation Physics, Lund, Lund University, Lund, Sweden.
Lund University · SESkåne University Hospital · SE

Funding

Cancerfonden 180747Cancerfonden 21-1754-Pj01HFru Berta Kamprads Stiftelse BKS-2020-13-293
6 · The paper itself

Abstract

backgroundSemiconductor gamma-camera systems based on cadmium zinc telluride (CZT) detectors present new challenges due to an energy-response that includes effects of low-energy tailing. In particular, such energy tails produce effects that need to be considered when imaging radionuclides with multiple emissions such as [Formula: see text]. Monte Carlo simulation can be used to investigate the behaviour of such systems and optimise their use, provided that the detector model closely reflects the real physical detector. The aim of this work is to develop a CZT model applicable for simulation of CZT-based gamma cameras.

methodsThe equations describing the charge transport and signal induction are considered in three dimensions and are solved numerically, and the CZT model is then realised by coupling the detector-response to the photon-transport handled by the SIMIND Monte Carlo program. The CZT model is tuned to reproduce experimentally measured energy spectra of a hand-held gamma camera system for multiple radionuclides ([Formula: see text], [Formula: see text] and [Formula: see text]) and parallel-hole collimators (MEGP, LEHR) as well as an uncollimated system.

resultsOverall, the model results agree well with measurements across the range of experimental conditions. The applicability of the model is demonstrated by separating energy spectra into components to investigate the interference of high-energy photons on lower energy-windows, where pronounced effects of low-energy tailing for [Formula: see text] are observed.

conclusionsThe developed model provides understanding of the specifics of the camera response and is expected to be helpful for future optimisation of gamma camera applications.

Indexed as

CZTHandheld gamma cameraMolecular imagingMonte Carlo

Identifiers

PMID35526172
PMCPMC9081070
OpenAlexW4229334413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.