Evidence map›Paper›PMID 35525996›Full record

ArticleBiological research2022

A novel gene from the acidophilic bacterium Leptospirillum sp. CF-1 and its role in oxidative stress and chromate tolerance.

Rivera-Araya Javier, Riveros Matías, Ferrer Alonso, Chávez Renato, Levicán Gloria

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rivera-Araya JavierBiology Department, Faculty of Chemistry and Biology, University of Santiago of Chile (USACH), Santiago, Chile.
Riveros MatíasBiology Department, Faculty of Chemistry and Biology, University of Santiago of Chile (USACH), Santiago, Chile.
Ferrer AlonsoNúcleo de Química y Bioquímica, Facultad de Ciencias, Universidad Mayor, Santiago, Chile.
Chávez RenatoBiology Department, Faculty of Chemistry and Biology, University of Santiago of Chile (USACH), Santiago, Chile.
Levicán GloriaBiology Department, Faculty of Chemistry and Biology, University of Santiago of Chile (USACH), Santiago, Chile. gloria.levican@usach.cl.ORCID http://orcid.org/0000-0002-1275-7399
Universidad de Santiago de Chile · CLUniversidad Mayor · CL

Funding

Departamento de Investigaciones Científicas y Tecnológicas, Universidad de Santiago de Chile Proyecto POSTDOC_DICYT COD 022043CR_POSTDOCFondo Nacional de Desarrollo Científico y Tecnológico 1170799Fondo Nacional de Desarrollo Científico y Tecnológico 1211386
6 · The paper itself

Abstract

backgroundAcidophilic microorganisms like Leptospirillum sp. CF-1 thrive in environments with extremely low pH and high concentrations of dissolved heavy metals that can induce the generation of reactive oxygen species (ROS). Several hypothetical genes and proteins from Leptospirillum sp. CF-1 are known to be up-regulated under oxidative stress conditions.

resultsIn the present work, the function of hypothetical gene ABH19_09590 from Leptospirillum sp. CF-1 was studied. Heterologous expression of this gene in Escherichia coli led to an increase in the ability to grow under oxidant conditions with 5 mM K

conclusionsAltogether, these results suggest that the och operon plays a protective role against chromate and hydrogen peroxide and is an important mechanism required to face polyextremophilic conditions in acid environments.

Indexed as

ChromatesHydrogen PeroxideBacteriaBacterial ProteinsEscherichia coliOperonOxidative StressReactive Oxygen SpeciesBacterial ProteinsChromatesHydrogen PeroxideReactive Oxygen SpeciesChromateHydrogen peroxideHypothetical proteinsLeptospirillumOch operonOxidative stress

Identifiers

PMID35525996
PMCPMC9080137
OpenAlexW4229037256

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.