Evidence map›Paper›PMID 35525856›Full record

ArticleEsophagus : official journal of the Japan Esophageal Society2022

Real-world treatment patterns and outcomes in Japanese patients with cervical esophageal cancer.

Kazuchika Ohno, Motomi Nasu, Hidetoshi Matsui, Yoshifumi Baba, Takushi Yasuda, Jun Sakuma, Kenichiro Ikeda, Takashi Maruo, Takumi Okuda, Norihiko Narita and 14 more

Abstract read
PubMed Publisher
In one paragraph

Article in Esophagus : official journal of the Japan Esophageal Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Kazuchika OhnoDepartment of Head and Neck Surgery, Tokyo Medical and Dental University, Tokyo, Japan. ohno.hns@tmd.ac.jp.ORCID 0000-0001-6826-799X
Motomi NasuDepartment of Esophageal and Gastroenterological Surgery, Juntendo University Faculty of Medicine, Tokyo, Japan.
Hidetoshi MatsuiDepartment of Head and Neck Cancer, Hyogo Cancer Center, Akashi, Japan.
Yoshifumi BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan.
Takushi YasudaDepartment of Surgery, School of Medicine, Kinki University, Osaka, Japan.
Jun SakumaDepartment of Surgery, NTT Medical Center Tokyo, Tokyo, Japan.
Kenichiro IkedaDepartment of Otolaryngology, School of Medicine, Showa University, Tokyo, Japan.
Takashi MaruoDepartment of Otolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Takumi OkudaDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Miyazaki University, Miyazaki, Japan.
Norihiko NaritaDepartment of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Fukui University, Fukui, Japan.
Hisayuki KatoDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.
Taiji KawasakiDepartment of Otolaryngology, Japanese Red Cross Shizuoka Hospital, Shizuoka, Japan.
Hiroshi SatoDivision of Digestive Surgery, Department of Surgery, International Medical Center, Saitama Medical University, Hidaka, Japan.
Kunihiko TokashikiDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.
Naoki AkisadaDivision of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime, Japan.
Hajime IshinagaDepartment of Otorhinolaryngology-Head and Neck Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Ken AkashiDepartment of Otolaryngology, Kameda Medical Center, Chiba, Japan.
Kenji OkamiDepartment of Otolaryngology, School of Medicine, Tokai University, Isehara, Japan.
Kosuke MurayamaDepartment of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Soichiro YamamotoDepartment of Gastrointestinal Surgery, Tokai University Hachioji Hospital, Tokyo, Japan.
Yuji KumakuraDepartment of Surgery, Fujioka General Hospital, Fujioka, Gunma, Japan.
Kenro KawadaDepartment of Gastrointestinal Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Akihiro ShiotaniDepartment of Otolaryngology-Head and Neck Surgery, National Defense Medical College, Saitama, Japan.
Takahiro AsakageDepartment of Head and Neck Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical esophageal cancer (CEC) carries a poor prognosis; however, due to its low incidence, optimal treatment for CEC remains to be established. The purpose of this study was to clarify the current status of treatment of CEC in Japan and obtain evidence for establishing the appropriate treatment method. PATIENTS AND

methodsWe asked specialist training facilities accredited by the Japanese Broncho-Esophageal Society to register data on CEC cases that received curative treatment from January 2009 to December 2014, and conducted a retrospective review of the clinical data of 302 cases registered from 27 facilities.

resultsIn regard to the initial therapy, of the 302 patients, 33 had undergone endoscopic resection, 41 had undergone surgery, 67 had received induction chemotherapy (IC), and 143 had received chemoradiotherapy (CRT). There were no significant differences in the 5-year overall survival rates among the patient groups that had received surgery, IC or CRT as the initial treatment; advanced stage and recurrent nerve invasion were identified as independent poor prognostic factors. Among the patients who had received IC or CRT as laryngeal-preserving surgery was not indicated at the time of the initial diagnosis, the functional laryngeal preservation rate at the end of the observation period was 34.8%.

conclusionEven in patients with advanced CEC, there is the possibility of preserving the larynx by adopting IC or CRT. However, if the laryngeal function cannot be preserved, there is a risk of complications from aspiration pneumonia, so that the choice of treatment should be made carefully.

Indexed as

Esophageal NeoplasmsLarynxChemoradiotherapyHumansInduction ChemotherapyJapanCervical esophageal cancerFunctional laryngeal preservationLaryngeal preservationMulticenter study

Identifiers

PMID35525856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.