ArticleBiomaterials advances2022
Polydopamine nanoparticles and hyaluronic acid hydrogels for mussel-inspired tissue adhesive nanocomposites.
Article in Biomaterials advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 48 citations in OpenAlex.
- Stage-adaptive integration of polydopamine promotes human pluripotent stem cell-derived alveolar organoids differentiation and maturation.Materials today. Bio · 2026Article
- An oral berberine nanocapsule platform orchestrates microbiota for potent gastric cancer chemotherapy.Journal of nanobiotechnology · 2026Article
- Human ES cell-derived MSC spheroids encapsulated in polydopamine nanoparticle-modified GelMA hydrogel enhance diabetic wound healing.Journal of nanobiotechnology · 2026Article
- Sealing Ability of Polydopamine-Coated Gutta-Percha With Bioceramic Sealer: An In Vitro Study.International journal of dentistry · 2026Article
- Enhanced ultraviolet barrier, antioxidant and antibacterial properties of chitosan-based films incorporated with caffeic acid-grafted inulin for strawberry preservation.Food chemistry: X · 2025Article
- Extracellular Matrix-Mediated Crosslinking of Adhesive Hyaluronic Acid Patch for Treating Volumetric Muscle Injury.Advanced healthcare materials · 2025Article
- Biomimetic intelligent nanoplatform with cascade amplification effect for tumor synergy therapy.Scientific reports · 2024Article
- Transcriptomic Approaches to Cardiomyocyte-Biomaterial Interactions: A Review.ACS biomaterials science & engineering · 2024Review
- Recent Development and Applications of Polydopamine in Tissue Repair and Regeneration Biomaterials.International journal of nanomedicine · 2024Review
- Multifunctional polydopamine - ZnBiomaterials advances · 2023Article
- Photocatalytic and Photothermal Antimicrobial Mussel-Inspired Nanocomposites for Biomedical Applications.International journal of molecular sciences · 2023Article
- Tissue adhesives for wound closure.Smart medicine · 2023Article
- Mussel-inspired nanoparticle composite hydrogels for hemostasis and wound healing.Frontiers in chemistry · 2023Review
- Multidynamic Osteogenic Differentiation by Effective Polydopamine Micro-Arc Oxide Manipulations.International journal of nanomedicine · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Bioadhesives are intended to facilitate the fast and efficient reconnection of tissues to restore their functionality after surgery or injury. The use of mussel-inspired hydrogel systems containing pendant catechol moieties is promising for tissue attachment under wet conditions. However, the adhesion strength is not yet ideal. One way to overcome these limitations is to add polymeric nanoparticles to create nanocomposites with improved adhesion characteristics. To further enhance adhesiveness, polydopamine nanoparticles with controlled size prepared using an optimized process, were combined with a mussel-inspired hyaluronic acid (HA) hydrogel to form a nanocomposite. The effects of sizes and concentrations of polydopamine nanoparticles on the adhesive profiles of mussel-inspired HA hydrogels were investigated. Results show that the inclusion of polydopamine nanoparticles in nanocomposites increased adhesion strength, as compared to the addition of poly (lactic-co-glycolic acid) (PLGA), and PLGA-(N-hydroxysuccinimide) (PLGA-NHS) nanoparticles. A nanocomposite with demonstrated cytocompatibility and an optimal lap shear strength (47 ± 3 kPa) was achieved by combining polydopamine nanoparticles of 200 nm (12.5% w/v) with a HA hydrogel (40% w/v). This nanocomposite adhesive shows its potential as a tissue glue for biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.