Evidence map›Paper›PMID 35525297›Full record

ArticleExperimental eye research2022

Artificial intelligence-based strategies to identify patient populations and advance analysis in age-related macular degeneration clinical trials.

Antonio Yaghy, Aaron Y Lee, Pearse A Keane, Tiarnan D L Keenan, Luisa S M Mendonca, Cecilia S Lee, Anne Marie Cairns, Joseph Carroll, Hao Chen, Julie Clark and 22 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Artificial intelligence for optimizing recruitment and retention in clinical trials: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Antonio YaghyNew England Eye Center, Tufts University Medical Center, Boston, MA, USA.
Aaron Y LeeDepartment of Ophthalmology, University of Washington, Seattle, WA, USA; Karalis Johnson Retina Center, Seattle, WA, USA.
Pearse A KeaneMoorfields Eye Hospital & UCL Institute of Ophthalmology, London, UK.
Tiarnan D L KeenanDivision of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Luisa S M MendoncaFederal University of Sao Paulo, Sao Paulo, Brazil.
Cecilia S LeeDepartment of Ophthalmology, University of Washington, Seattle, WA, USA; Karalis Johnson Retina Center, Seattle, WA, USA.
Anne Marie CairnsOptos Plc, Dunfermline, Scotland, United Kingdom.
Joseph CarrollDepartment of Ophthalmology & Visual Sciences, Medical College of Wisconsin, 925 N 87th Street, Milwaukee, WI, 53226, USA.
Hao ChenGenentech, South San Francisco, CA, USA.
Julie ClarkIveric Bio, Parsippany, NJ, USA.
Catherine A CukrasDivision of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Luis de SisternesCarl Zeiss Meditec, Inc, Dublin, CA, USA.
Amitha DomalpallyDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA.
Mary K DurbinCarl Zeiss Meditec, Inc, Dublin, CA, USA.
Kerry E GoetzOffice of the Director, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Felix GrassmannHealth and Medical University, Potsdam, Germany.
Jonathan L HainesDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Cleveland Institute of Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Naoto HondaNidek, CO. LTD, Aichi, Japan.
Zhihong Jewel HuDoheny Eye Institute, University of California, Los Angeles, CA, USA.
Christopher ModyHeidelberg Engineering, Heidelberg, Germany.
Luz D OrozcoDepartment of Bioinformatics, Genentech, South San Francisco, CA, 94080, USA.
Cynthia OwsleyDepartment of Ophthalmology and Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Stephen PoorDepartment of Ophthalmology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
Charles ReismanHeidelberg Engineering, Heidelberg, Germany.
Ramiro RibeiroApellis Pharmaceuticals, Waltham, MA, USA.
Srinivas R SaddaDoheny Eye Institute, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.
Sobha SivaprasadNIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital, London, UK.
Giovanni StaurenghiDepartment of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Italy.
Daniel Sw TingSingapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore.
Santa J TumminiaOffice of the Director, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Luca ZalunardoIcare USA Inc, Raleigh, NC, USA.
Nadia K WaheedNew England Eye Center, Tufts University Medical Center, Boston, MA, USA. Electronic address: nadiakwaheed@gmail.com.

Funding

Aging eyes and aging brains in studying alzheimer's disease: Modern ophthalmic data collection in the adult changes in thought (ACT) studyR01AG060942 · NIA · WASHINGTON UNIVERSITY · PI Cecilia Sungmin Lee · 2019 to 2026
$39.4M
Novel Optical Diagnostics with Optical Coherence TomographyR01EY011289 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI JAMES G FUJIMOTO · 1995 to 2026
$9.5M
Medical Research Council MR/T019050/1NEI NIH HHS R01 EY011289NIA NIH HHS R01 AG060942
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Artificial IntelligenceMacular DegenerationClinical Trials as TopicHumans

Identifiers

PMID35525297
PMCPMC9405680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.