Evidence map›Paper›PMID 35524932›Full record

ArticleClinical & experimental metastasis2022

FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.

Fangfang Zhao, Fangfang Ge, Minghua Xie, Zhenyu Li, Chunbao Zang, Lingsuo Kong, Youguang Pu, Xucai Zheng, Yiao Tan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical & experimental metastasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. mActa pharmaceutica Sinica. B · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. The diverse role of RNA methylation in esophageal cancer.Acta biochimica et biophysica Sinica · 2023
    Review
  7. Review
  8. Article
  9. The Role of mCancers · 2022
    Review
  10. METTL3/mFrontiers in pharmacology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fangfang Zhao *Department of Cancer Epigenetics Program, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China.
Fangfang Ge *Department of Provincial Clinical College, Wannan Medical College, Wuhu, 241002, Anhui, People's Republic of China.
Minghua Xie *Department of Thoracic Tumor Surgery Department, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China.
Zhenyu LiDepartment of Provincial Clinical College, Wannan Medical College, Wuhu, 241002, Anhui, People's Republic of China.
Chunbao ZangDepartment of Radiation Oncology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China.
Lingsuo KongDepartment of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China.
Youguang PuDepartment of Cancer Epigenetics Program, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China.
Xucai ZhengDepartment of Head, Neck and Breast Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China. zhengxucai@ustc.edu.cn.
Yiao TanDepartment of Urology Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei, 230031, Anhui, People's Republic of China. tanyiaoa@ustc.edu.cn.ORCID http://orcid.org/0000-0003-1594-3768
University of Science and Technology of China · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N

Indexed as

Alpha-Ketoglutarate-Dependent Dioxygenase FTOErb-b2 Receptor Tyrosine KinasesEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaDemethylationHumansRNA, MessengerAlpha-Ketoglutarate-Dependent Dioxygenase FTOERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFTO protein, humanRNA, MessengerERBB2Esophageal squamous cell carcinomaFTON6-methyladenosine (m6A) modificationYTHDF1

Identifiers

PMID35524932
PMCPMC9338917
OpenAlexW4229041700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.