Evidence map›Paper›PMID 35524706›Full record

ArticleMedical physics2022

Automatic stent recognition using perceptual attention U-net for quantitative intrafraction motion monitoring in pancreatic cancer radiotherapy.

Xiuxiu He, Weixing Cai, Feifei Li, Pengpeng Zhang, Marsha Reyngold, John J Cuaron, Laura I Cerviño, Tianfang Li, Xiang Li

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiuxiu HeDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Weixing CaiDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Feifei LiDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Pengpeng ZhangDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Marsha ReyngoldDepartment of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
John J CuaronDepartment of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Laura I CerviñoDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Tianfang LiDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Xiang LiDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748NIH/NCI Cancer Center Support Grant/Core Grant P30CA008748
6 · The paper itself

Abstract

purposeStent has often been used as an internal surrogate to monitor intrafraction tumor motion during pancreatic cancer radiotherapy. Based on the stent contours generated from planning CT images, the current intrafraction motion review (IMR) system on Varian TrueBeam only provides a tool to verify the stent motion visually but lacks quantitative information. The purpose of this study is to develop an automatic stent recognition method for quantitative intrafraction tumor motion monitoring in pancreatic cancer treatment.

methodsA total of 535 IMR images from 14 pancreatic cancer patients were retrospectively selected in this study, with the manual contour of the stent on each image serving as the ground truth. We developed a deep learning-based approach that integrates two mechanisms that focus on the features of the segmentation target. The objective attention modeling was integrated into the U-net framework to deal with the optimization difficulties when training a deep network with 2D IMR images and limited training data. A perceptual loss was combined with the binary cross-entropy loss and a Dice loss for supervision. The deep neural network was trained to capture more contextual information to predict binary stent masks. A random-split test was performed, with images of ten patients (71%, 380 images) randomly selected for training, whereas the rest of four patients (29%, 155 images) were used for testing. Sevenfold cross-validation of the proposed PAUnet on the 14 patients was performed for further evaluation.

resultsOur stent segmentation results were compared with the manually segmented contours. For the random-split test, the trained model achieved a mean (±standard deviation) stent Dice similarity coefficient (DSC), 95% Hausdorff distance (HD95), the center-of-mass distance (CMD), and volume difference

conclusionWe developed a novel deep learning-based approach to automatically segment the stent from IMR images, demonstrated its clinical feasibility, and validated its accuracy compared to manual segmentation. The proposed technique could be a useful tool for quantitative intrafraction motion monitoring in pancreatic cancer radiotherapy.

Indexed as

Image Processing, Computer-AssistedPancreatic NeoplasmsAttentionHumansRetrospective StudiesStentsIMRintrafraction motion monitoringradiotherapysegmentation

Identifiers

PMID35524706
PMCPMC9827417
OpenAlexW4229082742

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.