Evidence map›Paper›PMID 35524618›Full record

ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2022

Patterns and correlates of patient-reported helpfulness of treatment for common mental and substance use disorders in the WHO World Mental Health Surveys.

Ronald C Kessler, Alan E Kazdin, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Yasmin A Altwaijri, Laura H Andrade, Corina Benjet, Chrianna Bharat, Guilherme Borges and 53 more

Open access · bronzeAbstract read
In one paragraph

Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
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  4. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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  11. Achieving equality, inclusiveness, and cultural sensitivity in mental health (EDIT).World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
    Article
  12. The aggregation of marginal gains: a pragmatic philosophy of clinical care in psychiatry.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
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  15. Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  16. Review
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  18. Article
  19. Review
  20. The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

63 authors at 20 institutions in 28 countries.

Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Alan E KazdinDepartment of Psychology, Yale University, New Haven, CT, USA.
Sergio Aguilar-GaxiolaCenter for Reducing Health Disparities, UC Davis Health System, Sacramento, CA, USA.
Ali Al-HamzawiCollege of Medicine, Al-Qadisiya University, Diwaniya Governorate, Iraq.
Jordi AlonsoHealth Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain.
Yasmin A AltwaijriEpidemiology Section, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Laura H AndradeNúcleo de Epidemiologia Psiquiátrica - LIM 23, Instituto de Psiquiatria Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Corina BenjetDepartment of Epidemiologic and Psychosocial Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
Chrianna BharatNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.
Guilherme BorgesDepartment of Epidemiologic and Psychosocial Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
Ronny BruffaertsUniversitair Psychiatrisch Centrum - Katholieke Universiteit Leuven, Leuven, Belgium.
Brendan BuntingSchool of Psychology, Ulster University, Londonderry, UK.
José Miguel Caldas de AlmeidaLisbon Institute of Global Mental Health and Chronic Diseases Research Center, NOVA University of Lisbon, Lisbon, Portugal.
Graça CardosoLisbon Institute of Global Mental Health and Chronic Diseases Research Center, NOVA University of Lisbon, Lisbon, Portugal.
Wai Tat ChiuDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Alfredo CíaAnxiety Disorders Research Center, Buenos Aires, Argentina.
Marius CiutanNational School of Public Health, Management and Professional Development, Bucharest, Romania.
Louisa DegenhardtNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.
Giovanni de GirolamoIRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Peter de JongeDepartment of Developmental Psychology, University of Groningen, Groningen, The Netherlands.
Ymkje Anna de VriesDepartment of Developmental Psychology, University of Groningen, Groningen, The Netherlands.
Silvia FlorescuNational School of Public Health, Management and Professional Development, Bucharest, Romania.
Oye GurejeDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
Josep Maria HaroParc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain.
Meredith G HarrisSchool of Public Health, University of Queensland, Herston, and Queensland Centre for Mental Health Research, Wacol, QLD, Australia.
Chiyi HuShenzhen Institute of Mental Health and Shenzhen Kangning Hospital, Shenzhen, China.
Aimee N KaramInstitute for Development, Research, Advocacy and Applied Care, Beirut, Lebanon.
Elie G KaramInstitute for Development, Research, Advocacy and Applied Care, Beirut, Lebanon.
Georges KaramInstitute for Development, Research, Advocacy and Applied Care, Beirut, Lebanon.
Norito KawakamiDepartment of Mental Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Andrzej KiejnaPsychology Research Unit for Public Health, WSB University, Torun, Poland.
Viviane Kovess-MasfetyLaboratoire de Psychopathologie et Processus de Santé EA 4057, Université de Paris, Paris, France.
Sing LeeDepartment of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong.
Victor MakanjuolaDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
John J McGrathSchool of Public Health, University of Queensland, Herston, and Queensland Centre for Mental Health Research, Wacol, QLD, Australia.
Maria Elena Medina-MoraDepartment of Epidemiologic and Psychosocial Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
Jacek MoskalewiczInstitute of Psychiatry and Neurology, Warsaw, Poland.
Fernando Navarro-MateuUnidad de Docencia, Investigación y Formación en Salud Mental, Universidad de Murcia, Murcia, Spain.
Andrew A NierenbergDauten Family Center for Bipolar Treatment Innovation, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Daisuke NishiDepartment of Mental Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Akin OjagbemiDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
Bibilola D OladejiDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
Siobhan O'NeillSchool of Psychology, Ulster University, Londonderry, UK.
José Posada-VillaColegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia.
Victor Puac-PolancoDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Charlene RapseyDepartment of Psychological Medicine, University of Otago, Dunedin, New Zealand.
Ayelet Meron RuscioDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Kate M ScottDepartment of Psychological Medicine, University of Otago, Dunedin, New Zealand.
Tim SladeMatilda Centre for Research in Mental Health and Substance Use, University of Sydney, Sydney, Australia.
Juan Carlos StagnaroDepartamento de Psiquiatría y Salud Mental, Universidad de Buenos Aires, Buenos Aires, Argentina.
Dan J SteinDepartment of Psychiatry & Mental Health and South African Medical Council Research Unit on Risk and Resilience in Mental Disorders, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Hisateru TachimoriNational Institute of Mental Health, National Center for Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Margreet Ten HaveTrimbos-Instituut, Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands.
Yolanda TorresCenter for Excellence on Research in Mental Health, CES University, Medellin, Colombia.
Maria Carmen VianaDepartment of Social Medicine, Postgraduate Program in Public Health, Federal University of Espírito Santo, Vitoria, Brazil.
Daniel V VigoDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
David R WilliamsDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Bogdan WojtyniakCentre of Monitoring and Analyses of Population Health, National Institute of Public Health - National Research Institute, Warsaw, Poland.
Miguel XavierLisbon Institute of Global Mental Health and Chronic Diseases Research Center, NOVA University of Lisbon, Lisbon, Portugal.
Zahari ZarkovDepartment of Mental Health, National Center of Public Health and Analyses, Sofia, Bulgaria.
Hannah N ZiobrowskiDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
WHO World Mental Health Survey collaborators
Harvard University · USUniversity College Hospital, Ibadan · NGInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXUniversity of Lisbon · PTDepartment of Health · IENational School of Public Health, Management and Professional Development · ROSaint George Hospital · LBThe University of Queensland · AUUniversity of Groningen · NLUniversity of Otago · NZUniversity of Ulster · GBUNSW Sydney · AUCenter for Anxiety and Depression · USCentro de Investigación Biomédica en Red de Salud Mental · ESCentro San Giovanni di Dio Fatebenefratelli · ITChinese University of Hong Kong · HKHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRHospital Del Mar · ESInstitute for Development, Research, Advocacy and Applied Care · LBInstitute of Psychiatry and Neurology · PL

Funding

Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
World Mental Health Consortium Annual Meetings 2008-2012U13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2008 to 2012
$647k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481NIDA NIH HHS R01 DA016558NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R13 MH066849NIMH NIH HHS U13 MH066849
6 · The paper itself

Abstract

Patient-reported helpfulness of treatment is an important indicator of quality in patient-centered care. We examined its pathways and predictors among respondents to household surveys who reported ever receiving treatment for major depression, generalized anxiety disorder, social phobia, specific phobia, post-traumatic stress disorder, bipolar disorder, or alcohol use disorder. Data came from 30 community epidemiological surveys - 17 in high-income countries (HICs) and 13 in low- and middle-income countries (LMICs) - carried out as part of the World Health Organization (WHO)'s World Mental Health (WMH) Surveys. Respondents were asked whether treatment of each disorder was ever helpful and, if so, the number of professionals seen before receiving helpful treatment. Across all surveys and diagnostic categories, 26.1% of patients (N=10,035) reported being helped by the very first professional they saw. Persisting to a second professional after a first unhelpful treatment brought the cumulative probability of receiving helpful treatment to 51.2%. If patients persisted with up through eight professionals, the cumulative probability rose to 90.6%. However, only an estimated 22.8% of patients would have persisted in seeing these many professionals after repeatedly receiving treatments they considered not helpful. Although the proportion of individuals with disorders who sought treatment was higher and they were more persistent in HICs than LMICs, proportional helpfulness among treated cases was no different between HICs and LMICs. A wide range of predictors of perceived treatment helpfulness were found, some of them consistent across diagnostic categories and others unique to specific disorders. These results provide novel information about patient evaluations of treatment across diagnoses and countries varying in income level, and suggest that a critical issue in improving the quality of care for mental disorders should be fostering persistence in professional help-seeking if earlier treatments are not helpful.

Indexed as

anxiety disordersHelpfulness of treatmentheterogeneity of treatment effectsmood disorderspatient-centered carepost-traumatic stress disorderprecision psychiatryprofessional help-seekingsubstance use disorderstreatment adher­ence

Identifiers

PMID35524618
PMCPMC9077614
OpenAlexW4229063326

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