Evidence map›Paper›PMID 35524293›Full record

ArticleBMC musculoskeletal disorders2022

Automatic segmentation model of intercondylar fossa based on deep learning: a novel and effective assessment method for the notch volume.

Mifang Li, Hanhua Bai, Feiyuan Zhang, Yujia Zhou, Qiuyu Lin, Quan Zhou, Qianjin Feng, Lingyan Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mifang Li *Southern Medical University, 1838 shatai Road, Baiyun District, Guangzhou, 510515, Guangdong province, China.
Hanhua Bai *Southern Medical University, 1838 shatai Road, Baiyun District, Guangzhou, 510515, Guangdong province, China.
Feiyuan ZhangDepartment of Medical Imaging, The Third Affiliated Hospital, Southern Medical University, 183 Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong province, China.
Yujia ZhouDepartment of Biomedical Engineering, Southern Medical University, 1838 shatai Road, Baiyun District, Guangzhou, 510515, Guangdong province, China.
Qiuyu LinDepartment of Medical Imaging, The Third Affiliated Hospital, Southern Medical University, 183 Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong province, China.
Quan ZhouDepartment of Medical Imaging, The Third Affiliated Hospital, Southern Medical University, 183 Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong province, China. zhouquan3777@smu.edu.cn.
Qianjin FengSouthern Medical University, 1838 shatai Road, Baiyun District, Guangzhou, 510515, Guangdong province, China. fengqj@fimmu.com.
Lingyan ZhangSouthern Medical University, 1838 shatai Road, Baiyun District, Guangzhou, 510515, Guangdong province, China. 18819818005@163.com.ORCID http://orcid.org/0000-0002-6196-4220
Third Affiliated Hospital of Southern Medical University · CNSouthern Medical University · CNLonggang Central Hospital · CN

Funding

Bureau of Science and Technology Innovation of Longgang District LGWJ2021-25National Natural Science Foundation of China 81801780National Natural Science Foundation of China 81974275
6 · The paper itself

Abstract

backgroundNotch volume is associated with anterior cruciate ligament (ACL) injury. Manual tracking of intercondylar notch on MR images is time-consuming and laborious. Deep learning has become a powerful tool for processing medical images. This study aims to develop an MRI segmentation model of intercondylar fossa based on deep learning to automatically measure notch volume, and explore its correlation with ACL injury.

methodsThe MRI data of 363 subjects (311 males and 52 females) with ACL injuries incurred during non-contact sports and 232 subjects (147 males and 85 females) with intact ACL were retrospectively analyzed. Each layer of intercondylar fossa was manually traced by radiologists on axial MR images. Notch volume was then calculated. We constructed an automatic segmentation system based on the architecture of Res-UNet for intercondylar fossa and used dice similarity coefficient (DSC) to compare the performance of segmentation systems by different networks. Unpaired t-test was performed to determine differences in notch volume between ACL-injured and intact groups, and between males and females.

resultsThe DSCs of intercondylar fossa based on different networks were all more than 0.90, and Res-UNet showed the best performance. The notch volume was significantly lower in the ACL-injured group than in the control group (6.12 ± 1.34 cm

conclusionUsing a deep neural network to segment intercondylar fossa automatically provides a technical support for the clinical prediction and prevention of ACL injury and re-injury after surgery.

Indexed as

Anterior Cruciate Ligament InjuriesDeep LearningAnterior Cruciate LigamentFemaleFemurHumansKnee JointMagnetic Resonance ImagingMaleRetrospective StudiesAnterior cruciate ligament injuryDeep learningIntercondylar fossaMagnetic resonance imaging

Identifiers

PMID35524293
PMCPMC9074347
OpenAlexW4229033923

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.