Evidence map›Paper›PMID 35524233›Full record

ArticleBMC surgery2022

Chylous ascites with lymphatic leakage localization: technical aspects and clinical applications.

Chaoxiang Lu, Lei Wang, Qi Gao

Abstract read
In one paragraph

Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chaoxiang Lu *Department of Neonatal Surgery, Xi'an Children's Hospital & The Affiliated Children Hospital of Xi'an Jiaotong University, No. 69, Xijuyuan Lane ,Lianhu District, Xi'an, Shaanxi, 710003, China.
Lei Wang *Department of Neonatal Surgery, Xi'an Children's Hospital & The Affiliated Children Hospital of Xi'an Jiaotong University, No. 69, Xijuyuan Lane ,Lianhu District, Xi'an, Shaanxi, 710003, China.
Qi GaoDepartment of Neonatal Surgery, Xi'an Children's Hospital & The Affiliated Children Hospital of Xi'an Jiaotong University, No. 69, Xijuyuan Lane ,Lianhu District, Xi'an, Shaanxi, 710003, China. gaoqixjtcom@stu.xjtu.edu.cn.

Funding

the Basic Research Program of Natural Science in Shaanxi Province 2020JQ-931Xi'an "Science and Technology"+Action Plan Medical Research Project 2019114613YX001SF 042(6)
6 · The paper itself

Abstract

backgroundCarbon nanoparticle suspension (CNS) was applied to locate the lymphatic leakage in chylous ascites (CA). However, the flow speed and distance of the CNS were particularly decreased in the following two cases (patient 5 and 6). This study aimed to investigate and improve the flow speed and distance of the CNS via a rat model.

methodsSeven patients with CA were accepted for surgery in the past two years. Clinical data were recorded. Rats were divided into two groups to confirm the hypothesis regarding whether accepting milk or orally administered food before surgery was the key factor in CA surgery with CNS. The animals were divided into 2 groups: experimental group of 5 rats receiving fat emulsion injection (2 g/kg) 30 min before the operation and control group of 5 rats receiving saline. We analyzed flow speed and distance of the CNS in two groups of rats. The hypothesis established was that CNS movements pattern differ depending on the degree of capillary lymph duct filling. Finally, the late case reconfirmed the hypothesis again.

resultsIn animal experiments, the CNS in the preoperative high-fat feeding group moved faster and over a longer distance than that in the control group (0.51 ± 0.09 cm vs. 0.19 ± 0.10 cm, respectively; p < 0.05). Based on this, the CNS was applied to the seventh patient, who had been given a diet with a slightly higher fat content 3 days before the operation, and marked improvement with a complete cure was recorded.

conclusionsThe capillary lymph duct was beginning to swell after dietary intake. The dilation of the lymph vessel could make it easier for the CNS to move and reach the leakage.

Indexed as

Chylous AscitesLymphatic VesselsAnimalsHumansRatsCarbon Nanoparticle suspensionChylous ascitesLymphatic leakage localizationMedium-chain triglyceridesProlonged fasting

Identifiers

PMID35524233
PMCPMC9077892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.