Evidence map›Paper›PMID 35524209›Full record

ArticleBMC health services research2022

On prioritising global health's triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi.

Paul Kawale, Levi Kalitsilo, Jessie Mphande, Bayode Romeo Adegbite, Martin P Grobusch, Shevin T Jacob, Jamie Rylance, Nyovani J Madise

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. A Nation of Disasters: Lessons on Systemic Risks and Cascading Impacts From Malawi's COVID-19 Experience.Risk analysis : an official publication of the Society for Risk Analysis · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 6 countries.

Paul KawaleAfrican Institute for Development Policy, Lilongwe, Malawi. pkawale@kuhes.ac.mw.
Levi KalitsiloAfrican Institute for Development Policy, Lilongwe, Malawi.
Jessie MphandeAfrican Institute for Development Policy, Lilongwe, Malawi.
Bayode Romeo AdegbiteCentre de Recherches Médicales de Lambaréné (CERMEL) and African Partner Institution, Lambarene, Gabon.
Martin P GrobuschCentre de Recherches Médicales de Lambaréné (CERMEL) and African Partner Institution, Lambarene, Gabon.
Shevin T JacobLiverpool School of Tropical Medicine, Liverpool, UK.
Jamie RylanceLiverpool School of Tropical Medicine, Liverpool, UK.
Nyovani J MadiseAfrican Institute for Development Policy, Lilongwe, Malawi.
African Institute for Development Policy · MWLiverpool School of Tropical Medicine · GBUniversity of Amsterdam · NLUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis causes 20% of global deaths, particularly among children and vulnerable populations living in developing countries. This study investigated how sepsis is prioritised in Malawi's health system to inform health policy. In this mixed-methods study, twenty multisectoral stakeholders were qualitatively interviewed and asked to quantitatively rate the likelihood of sepsis-related medium-term policy outcomes being realised. Respondents indicated that sepsis is not prioritised in Malawi due to a lack of local sepsis-related evidence and policies. However, they highlighted strong linkages between sepsis and maternal health, antimicrobial resistance and COVID-19, which are already existing national priorities, and offers opportunities for sepsis researchers as policy entrepreneurs. To address the burden of sepsis, we recommend that funding should be channelled to the generation of local evidence, evidence uptake, procurement of resources and treatment of sepsis cases, development of appropriate indicators for sepsis, adherence to infection prevention and control measures, and antimicrobial stewardship.

Indexed as

COVID-19SepsisAnti-Bacterial AgentsChildDrug Resistance, BacterialFemaleGlobal HealthHumansMalawiAnti-Bacterial AgentsAntimicrobial resistanceCOVID-19Health priorityHealth systemSepsis

Identifiers

PMID35524209
PMCPMC9076498
OpenAlexW4229332904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.