ReviewNature neuroscience2022
Genetics and neurobiology of eating disorders.
Review in Nature neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Common and distinct neural patterns of gray matter alterations in adults with anorexia nervosa and obsessive-compulsive disorder.European archives of psychiatry and clinical neuroscience · 2025Pooled it
- Efficacy of naltrexone and bupropion combination in patients with binge eating disorder: a systematic review and meta-analysis.Eating and weight disorders : EWD · 2025Pooled it
- Neuroimaging and machine learning in eating disorders: a systematic review.Eating and weight disorders : EWD · 2025Pooled it
- Psychological Characteristics of Fathers of People With Bulimia Nervosa: A Systematic Review.The International journal of eating disorders · 2025Pooled it
- Comorbidity of binge eating disorder and other psychiatric disorders: a systematic review.BMC psychiatry · 2024Pooled it
- Similarities and differences between eating disorders and obsessive-compulsive disorder in childhood and adolescence: a systematic review.Frontiers in psychiatry · 2024Pooled it
- Effectiveness of written emotional disclosure interventions for eating disorders: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation.Health technology assessment (Winchester, England) · 2025Trial
- Integrated multi-omics and functional analyses reveal a GDCA-TGR5-mediated immunometabolic signature in anorexia nervosa.European archives of psychiatry and clinical neuroscience · 2026Article
- Eating Disorders and Parkinson's Disease-2: Genetic Epidemiology and Shared Genomics.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Bulimia nervosa.Nature reviews. Disease primers · 2026Review
- Collective responsibility and ecological thinking in eating disorders: moving beyond individualistic models of illness and recovery.Journal of eating disorders · 2026Article
- Regional gray matter alterations in anorexia nervosa: implications for subtype heterogeneity and clinical severity.Molecular psychiatry · 2026Article
- Psychological and clinical associations of adverse childhood experiences in Chinese patients with eating disorders.Journal of eating disorders · 2026Article
- Time to Address Eating Disorder Risk Among Medical Students.Behavioral sciences (Basel, Switzerland) · 2026Review
- Advancing translational research in binge-eating: Integrating insights from clinical practice into animal models.Translational psychiatry · 2026Review
- MidbrainbioRxiv : the preprint server for biology · 2026Article
- The longitudinal impact of individual and parental emotional factors and individual behavioral factors on weight and disordered eating: A scoping review.Reviews in endocrine & metabolic disorders · 2026Review
- GLP-1 is associated with perfectionism in Swedish women with anorexia nervosa, independent of BMI.Eating and weight disorders : EWD · 2026Article
- Delayed diagnosis of anorexia nervosa following childhood cancer treatment: a case report and literature review.Journal of eating disorders · 2026Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Eating disorders (anorexia nervosa, bulimia nervosa and binge-eating disorder) are a heterogeneous class of complex illnesses marked by weight and appetite dysregulation coupled with distinctive behavioral and psychological features. Our understanding of their genetics and neurobiology is evolving thanks to global cooperation on genome-wide association studies, neuroimaging, and animal models. Until now, however, these approaches have advanced the field in parallel, with inadequate cross-talk. This review covers overlapping advances in these key domains and encourages greater integration of hypotheses and findings to create a more unified science of eating disorders. We highlight ongoing and future work designed to identify implicated biological pathways that will inform staging models based on biology as well as targeted prevention and tailored intervention, and will galvanize interest in the development of pharmacologic agents that target the core biology of the illnesses, for which we currently have few effective pharmacotherapeutics.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.