Evidence map›Paper›PMID 35523935›Full record

ArticleScientific reports2022

End-of-life discussions reduce the utilization of life-sustaining treatments during the last three months of life in cancer patients.

Shang-Yih Chan, Yun-Ju Lai, Yu-Yen Chen, Shuo-Ju Chiang, Yi-Fan Tsai, Li-Fei Hsu, Pei-Hung Chuang, Chu-Chieh Chen, Yung-Feng Yen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Shang-Yih Chan *Department of Internal Medicine, Yangming Branch, Taipei City Hospital, Taipei, Taiwan.
Yun-Ju Lai *Department of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Yu-Yen Chen *School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Shuo-Ju ChiangDepartment of Cardiology, Yangming Branch, Taipei City Hospital, Taipei, Taiwan.
Yi-Fan TsaiDepartment of Nursing, Yangming Branch, Taipei City Hospital, Taipei, Taiwan.
Li-Fei HsuCollege of Public Health, National Taiwan University, Taipei, Taiwan.
Pei-Hung ChuangTaipei Association of Health and Welfare Data Science, Taipei, Taiwan.
Chu-Chieh Chen *Department of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Yung-Feng YenDepartment of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. yfyen1@gmail.com.
Ministry of Health and Welfare · TWNational Taipei University of Nursing and Health Science · TWChung Shan Medical University · TWNational Taiwan University · TWTaipei City Hospital · TWTaipei Medical University · TWUniversity of Taipei · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies to examine the impact of end-of-life (EOL) discussions on the utilization of life-sustaining treatments near death are limited and have inconsistent findings. This nationwide population-based cohort study determined the impact of EOL discussions on the utilization of life-sustaining treatments in the last three months of life in Taiwanese cancer patients. From 2012 to 2018, this cohort study included adult cancer patients, which were confirmed by pathohistological reports. Life-sustaining treatments during the last three months of life included cardiopulmonary resuscitation, intubation, and defibrillation. EOL discussions in cancer patients were confirmed by their medical records. Association of EOL discussions with utilization of life-sustaining treatments were assessed using multiple logistic regression. Of 381,207 patients, the mean age was 70.5 years and 19.4% of the subjects received life-sustaining treatments during the last three months of life. After adjusting for other covariates, those who underwent EOL discussions were less likely to receive life-sustaining treatments during the last three months of life compared to those who did not (Adjusted odds ratio [AOR] 0.87; 95% confidence interval [CI] 0.85-0.89). Considering the type of treatments, EOL discussions correlated with a lower likelihood of receiving cardiopulmonary resuscitation (AOR = 0.45, 95% CI 0.43-0.47), endotracheal intubation (AOR = 0.92, 95%CI 0.90-0.95), and defibrillation (AOR = 0.54, 95%CI 0.49-0.59). Since EOL discussions are associated with less aggressive care, our study supports the importance of providing these discussions to cancer patients during the EOL treatment.

Indexed as

NeoplasmsTerminal CareAdultAgedCohort StudiesDeathHumansLogistic Models

Identifiers

PMID35523935
PMCPMC9076633
OpenAlexW4229073883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.