ArticleNature communications2022
Genetic diversity of SARS-CoV-2 infections in Ghana from 2020-2021.
Abstract read
In one paragraph
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- From trial site to research emerging research hub: mapping Ghana's vaccine research ecosystem, 1977-2025.Health research policy and systems · 2026Review
- SARS CoV-2 seroprevalence and rising antibody titres across successive pandemic waves in accra, Ghana: August 2020 to January 2022.Scientific reports · 2026Article
- Two years of SARS-CoV-2 genomic surveillance capacity development in Guinea.Scientific reports · 2026Article
- Genomic diversity of SARS-CoV-2 carriage in a cohort of schoolchildren in Côte d'ivoire during COVID-19 pandemics: insights from pre-delta emergence.BMC infectious diseases · 2026Article
- Provincial stratification and equity-weighted cost-effectiveness of malaria vaccines in Zambia under climate variability.BMJ public health · 2026Article
- Genomic diversity and surveillance of SARS-CoV-2 in Nigeria.BMC genomics · 2025Article
- Adults in Ghana generate higher and more durable neutralising antibody titres following primary course COVID-19 vaccination than matched UK adults: The HERITAGE Study.BMC medicine · 2025Article
- Unveiling the Dynamics of SARS-CoV-2 Gamma and Delta Waves in Paraná, Brazil - Delta Displacing a Persistent Gamma Through Alternative Routes of Dispersal.Journal of medical virology · 2025Article
- Article
- Helminth Seropositivity Inversely Correlated with Th1 and Th17 Cytokines and Severe COVID-19.Vaccines · 2025Article
- Tracking the genetic diversity of SARS-CoV-2 variants in Nicaragua throughout the COVID-19 pandemic.Scientific reports · 2025Article
- Genomic and epidemiological analysis of SARS-CoV-2 variants isolated in Guinea: a routine sequencing implementation.BMC infectious diseases · 2025Article
- Modelling the impact of vaccination on COVID-19 in African countries.PLoS computational biology · 2024Article
- Cellular immune response to SARS-CoV-2 and clinical presentation in individuals exposed to endemic malaria.Cell reports · 2024Article
- Detection of SARS-CoV-2 Variants Imported Through Land Borders at the Height of the COVID-19 Pandemic in Ghana, 2022.Cureus · 2024Article
- Genomic Surveillance and Mutation Analysis of SARS-CoV-2 Variants among Patients in Saudi Arabia.Microorganisms · 2024Article
- Molecular Epidemiology of SARS-CoV-2 within Accra Metropolis Postlockdown.Advances in virology · 2024Article
- Genetic diversity and genomic epidemiology of SARS-CoV-2 during the first 3 years of the pandemic in Morocco: comprehensive sequence analysis, including the unique lineage B.1.528 in Morocco.Access microbiology · 2024Article
- First Molecular Detection of SARS-CoV-2 in Sewage and Wastewater in Ghana.BioMed research international · 2024Article
- Epidemiological overlaps in COVID-19 and malaria within healthcare and community settings of Southern Ghana.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
56 authors.
Collins M Morang'aWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.ORCID 0000-0002-6988-150X
Joyce M NgoiWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Jones GyamfiUniversity of Health and Allied Sciences COVID-19 Testing and Research Centre, Ho, Ghana.
Dominic S Y AmuzuWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Benjamin D NuerteyTamale Teaching Hospital Intensive Care Unit, Ghana Health Service, Tamale, Ghana.ORCID 0000-0003-4946-508X
Philip M SogloWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Vincent AppiahWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Ivy A AsanteNoguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana.
Paul Owusu-OduroLEDing Medical Laboratory, Accra, Ghana.
Samuel ArmooBiomedical and Public Health Research Unit, Council for Scientific and Industrial Research, Accra, Ghana.
Dennis Adu-GyasiKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Ghana.ORCID 0000-0002-9449-2565
Nicholas AmoakoWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Joseph Oliver-CommeyGhana Infectious Disease Centre, Accra, Ghana.
Michael OwusuKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0001-5066-150X
Augustina SylverkenKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Edward D FentengAccra Veterinary Laboratory, Veterinary Services Directorate, Accra, Ghana.
Violette V M'cormackWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Frederick Tei-MayaWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.ORCID 0000-0003-4507-1788
Evelyn B QuansahWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Reuben Ayivor-DjanieUniversity of Health and Allied Sciences COVID-19 Testing and Research Centre, Ho, Ghana.ORCID 0000-0003-0323-5473
Enock K AmoakoWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Isaac T OgbeWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Bright K YemiWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Israel Osei-WusuWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.ORCID 0000-0002-7329-7197
Deborah N A MettleWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Samirah SaiidWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Kesego TapelaWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Francis DzabengWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Vanessa MagnussenWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Jerry QuayeWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.ORCID 0000-0001-7177-997X
Precious C OpurumWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Rosina A CarrUniversity of Health and Allied Sciences COVID-19 Testing and Research Centre, Ho, Ghana.ORCID 0000-0001-8391-5633
Patrick T AbabioAccra Veterinary Laboratory, Veterinary Services Directorate, Accra, Ghana.
Abdul-Karim AbassTamale Public Health and Reference Laboratory, Ghana Health Service, Tamale, Ghana.
Samuel K AkoriyeaInstitutional Care Division (ICD), Ghana Health Service, Accra, Ghana.
Emmanuella AmoakoCape Coast Teaching Hospital, Ghana Health Service, Cape Coast, Ghana.
Frederick Kumi-AnsahCape Coast Teaching Hospital, Ghana Health Service, Cape Coast, Ghana.ORCID 0000-0001-5094-5035
Oliver D BoakyeTakoradi Veterinary Services Department, Ghana Health Service, Takoradi, Ghana.
Dam K MibutTamale Teaching Hospital Intensive Care Unit, Ghana Health Service, Tamale, Ghana.
Theophilus OdoomTakoradi Veterinary Services Department, Ghana Health Service, Takoradi, Ghana.
Lawrence Ofori-BoaduGa East Municipal Hospital, Ghana Health Service, Accra, Ghana.
Emmanuel Allegye-CudjoePong-Tamale Central Veterinary Laboratory, National Veterinary Services Directorate, Tamale, Ghana.
Sylvester DassahNavrongo Health Research Centre, Research and Development Division, Ghana Health Service, Navrongo, Ghana.
Victor AsoalaNavrongo Health Research Centre, Research and Development Division, Ghana Health Service, Navrongo, Ghana.
Kwaku P AsanteKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Ghana.
Richard O PhillipsKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Mike Y Osei-AtweneboanaBiomedical and Public Health Research Unit, Council for Scientific and Industrial Research, Accra, Ghana.
John O GyapongUniversity of Health and Allied Sciences COVID-19 Testing and Research Centre, Ho, Ghana.
Patrick Kuma-AboagyeGhana Health Service, Accra, Ghana.
William K AmpofoNoguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana.
Kwabena O DueduUniversity of Health and Allied Sciences COVID-19 Testing and Research Centre, Ho, Ghana.ORCID 0000-0001-5816-5172
Nicaise T NdamInstitut de Recherche pour le Développement, Marseille, France.
Yaw BediakoWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Peter K QuashieWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana. pquashie@ug.edu.gh.ORCID 0000-0003-4114-5460
Lucas N Amenga-EtegoWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana. lamenga-etego@ug.edu.gh.ORCID 0000-0003-4468-0506
Gordon A AwandareWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana. gawandare@ug.edu.gh.ORCID 0000-0002-8793-3641
Funding
Department of Health 17.63.91Medical Research Council MR/J01477X/1Medical Research Council MR/P028071/1Wellcome Trust 107755/Z/15/Z
Abstract
The COVID-19 pandemic is one of the fastest evolving pandemics in recent history. As such, the SARS-CoV-2 viral evolution needs to be continuously tracked. This study sequenced 1123 SARS-CoV-2 genomes from patient isolates (121 from arriving travellers and 1002 from communities) to track the molecular evolution and spatio-temporal dynamics of the SARS-CoV-2 variants in Ghana. The data show that initial local transmission was dominated by B.1.1 lineage, but the second wave was overwhelmingly driven by the Alpha variant. Subsequently, an unheralded variant under monitoring, B.1.1.318, dominated transmission from April to June 2021 before being displaced by Delta variants, which were introduced into community transmission in May 2021. Mutational analysis indicated that variants that took hold in Ghana harboured transmission enhancing and immune escape spike substitutions. The observed rapid viral evolution demonstrates the potential for emergence of novel variants with greater mutational fitness as observed in other parts of the world.
Indexed as
COVID-19SARS-CoV-2Genome, ViralGhanaHumansMutationPandemicsPhylogenySpike Glycoprotein, CoronavirusSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.