Evidence map›Paper›PMID 35523519›Full record

ArticleRMD open2022

Disparities in healthcare in psoriatic arthritis: an analysis of 439 patients from 13 countries.

Florian Lucasson, Uta Kiltz, Umut Kalyoncu, Ying Ying Leung, Penélope Palominos, Juan D Cañete, Rossana Scrivo, Andra Balanescu, Emanuelle Dernis, Sandra Meisalu and 13 more

Erratum issued Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in RMD open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03119805 (Defining Cut-off Values for Widely-used Composite Scores and Patient-reported Outcome Measures in Psoriatic Arthritis Corresponding to Remission and Flare Assessed by the Physician and the Patient), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03119805 completednot on this map

Defining Cut-off Values for Widely-used Composite Scores and Patient-reported Outcome Measures in Psoriatic Arthritis Corresponding to Remission and Flare Assessed by the Physician and the Patient

Typeobservational_patient_registrySponsorGroupe Hospitalier Pitie-SalpetriereRan2017 to 2018Enrolled466ConditionsPsoriatic Arthritis
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 19 institutions in 16 countries.

Florian LucassonINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, Paris, France flo.lucasson@hotmail.fr.ORCID 0000-0001-7479-1392
Uta KiltzHerne and Ruhr-Universität, Rheumazentrum Ruhrgebiet, Bochum, Germany.ORCID 0000-0001-5668-4497
Umut KalyoncuDepartment of Internal Medicine, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Ying Ying LeungDuke-NUS Medical School, Singapore General Hospital, Singapore.
Penélope PalominosRheumatology Department, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil.ORCID 0000-0003-0132-4325
Juan D CañeteServicio de Reumatología, Hospital Clínic and IDIBAPS, Barcelona, Spain.ORCID 0000-0003-2606-0573
Rossana ScrivoRheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza Università di Roma, Roma, Italy.
Andra BalanescuDepartment of Internal Medicine and Rheumatology, "Sf. Maria" Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Emanuelle DernisRheumatology Unit, Le Mans General Hospital, Le Mans, France.
Sandra MeisaluEast Tallinn Central Hospital, Tallinn, Estonia.
Adeline Ryussen-WitrandCentre d'Investigation Clinique de Toulouse CIC1436, Inserm, Paul Sabatier University, Toulouse University Hospital, Toulouse, France.ORCID 0000-0002-9815-2138
Martin SoubrierGabriel Montpied Hospital, Clermont-Ferrand, France.ORCID 0000-0001-9349-0720
Sibel Zehra AydinThe Ottawa Hospital Research Institute, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.ORCID 0000-0001-8792-4449
Lihi EderWomen's College Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1473-1715
Inna GaydukovaNorth-western State Medical University, St.Petersburg, Russian Federation.
Ennio LubranoAcademic Rheumatology Unit, Dipartimento di Medicina e Scienze della Salute "Vincenzo Tiberio", University of Molise, Campobasso, Italy.ORCID 0000-0001-6189-5328
Pascal RichetteService de Rhumatologie, Hopital Lariboisiere Centre Viggo Petersen, Paris, France.ORCID 0000-0003-2132-4074
Elaine HusniDepartment of Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, Ohio, USA.
Laura C CoatesNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-4756-663X
Maarten de WitPatient Research Partner, EULAR, Zaltbommel, The Netherlands.ORCID 0000-0002-8428-6354
Josef S SmolenDivision of Rheumatology, Department of Medicine 3, Medical University of Vienna, Wien, Austria.
Ana-Maria OrbaiDivision of Rheumatology, Psoriatic Arthritis Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-8644-8567
Laure GossecINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, INSERM, Sorbonne Universite, Paris, France.ORCID 0000-0002-4528-310X
Inserm · FRCenter for Rheumatology · USCarol Davila University of Medicine and Pharmacy · ROCentre Hospitalier du Mans · FRCleveland Clinic · USEast Tallinn Central Hospital · EEEuropean League Against Rheumatism · CHHospital de Clínicas de Porto Alegre · BRJohns Hopkins University · USNorth-Western State Medical University named after I.I. Mechnikov · RUNuffield Orthopaedic Centre · GBSapienza University of Rome · ITSingapore General Hospital · SGSociedad Española de Reumatología · ESUniversitätsklinik Marien Hospital Herne · DEUniversité Toulouse III - Paul Sabatier · FRUniversity of Molise · ITUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

Sample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CLIFTON O BINGHAM, Antony Rosen · 2016 to 2026
$8.9M
Targeting TNFR2 Pathways in Psoriatic DiseasesR01AR075777 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI CHANDRASEKHARAN, UNNIKRISHNAN M, HUSNI, ELAINE · 2019 to 2023
$1.8M
Department of HealthNIAMS NIH HHS P30 AR070254NIAMS NIH HHS R01 AR075777
6 · The paper itself

Abstract

objectivesPatient care can vary substantially by country. The objective was to explore differences in psoriatic arthritis (PsA) across countries for disease activity, impact and treatments.

methodsA cross-sectional analysis of 13 countries from the Remission/Flare in PsA study (NCT03119805) of consecutive adult patients with definite PsA was performed. Countries were classified into tertiles by gross domestic product (GDP)/capita. Disease activity (Disease Activity in PsA, DAPSA and Minimal Disease Activity, MDA) and their components, disease impact (patient-reported outcomes) and biological disease-modifying antirheumatic drugs (bDMARDs) were analysed per country and compared between the three tertiles of GDP/capita by parametric and non-parametric tests. We also explored the percentage of patients with significant disease activity (DAPSA >14) and no ongoing bDMARD prescription.

resultsIn 439 patients (50.6% male, mean age 52.3 years, mean disease duration 10.1 years), disease activity and disease impact were higher in the lowest GDP/capita countries. DAPSA remission and MDA were attained in the lowest tertile in 7.0% and 18.4% patients, vs 29.1% and 49.5% in the middle tertile and 16.8% and 41.3% in the high tertile, respectively (all p<0.001). bDMARDs use was similar in the tertiles (overall mean 61%). The overall rate of patients with DAPSA >14 and no bDMARDs was 18.5%, and was higher in lower GDP/capita countries (p=0.004).

conclusionPsA patients from countries with the lowest GDP/capita, despite similar use of bDMARDs, were more likely to have high disease activity and worse disease impact. There is a need for more equity in healthcare.

Indexed as

Arthritis, PsoriaticHealthcare DisparitiesAdultAntirheumatic AgentsCross-Sectional StudiesDelivery of Health CareFemaleHumansMaleMiddle AgedRemission InductionSeverity of Illness IndexTreatment OutcomeAntirheumatic AgentsArthritis, PsoriaticEpidemiologyOutcome Assessment, Health Care

Identifiers

PMID35523519
PMCPMC9083399
OpenAlexW4229049401

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.