Evidence map›Paper›PMID 35523480›Full record

ArticleRegional anesthesia and pain medicine2022

Postoperative opioid prescribing, use and pain trends following general surgery procedures: a retrospective cohort study among veterans comparing non-opioid versus chronic opioid users.

Josh Bleicher, Benjamin Sands Brooke, Kimberlee Bayless, Zachary Anderson, Julie Beckstrom, Chong Zhang, Angela P Presson, Lyen C Huang, Michael Jacob Buys

Open access · greenAbstract read
In one paragraph

Article in Regional anesthesia and pain medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Josh BleicherSurgery, University of Utah Health Hospitals and Clinics, Salt Lake City, Utah, USA.
Benjamin Sands BrookeSurgery, University of Utah Health Hospitals and Clinics, Salt Lake City, Utah, USA.
Kimberlee BaylessAnesthesiology, VA Salt Lake City Health Care System, Salt Lake City, Utah, USA.
Zachary AndersonAnesthesiology, VA Salt Lake City Health Care System, Salt Lake City, Utah, USA.
Julie BeckstromSurgery, University of Utah Health Hospitals and Clinics, Salt Lake City, Utah, USA.
Chong ZhangInternal Medicine-Epidemiology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Angela P PressonInternal Medicine-Epidemiology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Lyen C HuangSurgery, University of Utah Health Hospitals and Clinics, Salt Lake City, Utah, USA.
Michael Jacob BuysAnesthesiology, University of Utah Health Hospitals and Clinics, Salt Lake City, Utah, USA michael.buys@hsc.utah.edu.ORCID http://orcid.org/0000-0001-8222-1461
University of Utah Hospital · USUniversity of Utah · USVA Salt Lake City Healthcare System · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Vascular Health and Risk Factors in Children with Down SyndromeKL2TR002539 · NCATS · UNIVERSITY OF UTAH · PI MURTAUGH, MAUREEN A, NYGAARD, INGRID E · 2018 to 2022
$4.3M
NCATS NIH HHS KL2 TR002539NCATS NIH HHS UL1 TR002538
6 · The paper itself

Abstract

introductionUnderstanding postoperative opioid use patterns among different populations is key to developing opioid stewardship programs.

methodsWe performed a retrospective cohort study on opioid prescribing, use, and pain after general surgery procedures for patients cared for by a transitional pain service at a veterans administration hospital. Discharge opioid prescription quantity, 90-day opioid prescription, and patient reported outcome pain measures were compared between chronic opioid users and non-opioid users (NOU). Additionally, 90-day total opioid use was evaluated for NOU.

resultsOf 257 patients, 34 (13%) were on chronic opioid therapy, over 50% had a mental health disorder, and 29% had a history and/or presence of a substance use disorder. NOU were prescribed a median (IQR) of 10 (7, 12) tablets at discharge, while chronic opioid users were prescribed 6 (0, 12) tablets (p<0.001). 90-day opioid prescription (not including baseline opioid prescription for chronic users) was 10 (7, 15) and 6 (0, 12) tablets, respectively (p=0.001). There were no differences in changes in pain intensity or pain interference scores during recovery between groups. Median 90-day opioid use post discharge for NOU was 4 (0, 10) pills. DISCUSSION: Non-opioid and chronic opioid users required very few opioid pills following surgery, and patients on chronic opioid therapy quickly returned to their baseline opioid use after a small opioid prescription at discharge. There was no difference in pain recovery between groups. Opioid prescribing guidelines should include patients on chronic opioid therapy and could consider recommending a more conservative prescribing approach.

Indexed as

Acute PainAnalgesics, OpioidPain MeasurementPain, Postoperative

Identifiers

PMID35523480
PMCPMC10473845
OpenAlexW4229005214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.