Evidence map›Paper›PMID 35523135›Full record

ArticleCell stem cell2022

The amnion as a window into human pluripotency.

Brian J Cox, Amy Ralston

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Brian J CoxDepartments of Physiology and Obstetrics and Gynecology, University of Toronto, Toronto, ON, M5S1A8, Canada. Electronic address: b.cox@utoronto.ca.
Amy RalstonDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA. Electronic address: aralston@msu.edu.

Funding

Molecular mechanisms regulating formation of diverse stem cell progenitorsR35GM131759 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Amy Ralston · 2019 to 2026
$3.0M
NIGMS NIH HHS R35 GM131759
6 · The paper itself

Abstract

In this issue of Cell Stem Cell, a new study by Rostovskaya et al. (2022) uses human stem cells to understand the formation of the amnion, a vital extraembryonic tissue that encircles the fetus during gestation. They provide insight into human amnion formation and reveal differences in developmental competency of naive and primed human pluripotent stem cells.

Indexed as

AmnionPluripotent Stem CellsCell DifferentiationHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.