Evidence map›Paper›PMID 35523121›Full record

ArticleStructure (London, England : 1993)2022

One enzyme, many substrates: How the vaccinia virus enzyme D9 decaps host and viral mRNAs alike.

Vincent D Maciej, Sutapa Chakrabarti

Abstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The strategies and advances of mRNA translation booster.Asian journal of pharmaceutical sciences · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Vincent D MaciejInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Takustr. 6, D-14195 Berlin, Germany.
Sutapa ChakrabartiInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Takustr. 6, D-14195 Berlin, Germany. Electronic address: chakraba@zedat.fu-berlin.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The decapping enzyme D9 acts on host mRNA and viral double-stranded RNA to promote viral replication in host cells. In this issue of Structure, Peters et al. (2022) present crystal structures of m

Indexed as

Vaccinia virusViral ProteinsRNA, Double-StrandedRNA, MessengerVirus ReplicationRNA, Double-StrandedRNA, MessengerViral Proteins

Identifiers

PMID35523121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.