Evidence map›Paper›PMID 35523051›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2022

The Hospitalization Rate of Cerebral Venous Sinus Thrombosis before and during COVID-19 Pandemic Era: A Single-Center Retrospective Cohort Study.

Maryam Vasaghi Gharamaleki, Maryam Habibagahi, Etrat Hooshmandi, Reza Tabrizi, Shahram Arsang-Jang, Zohreh Barzegar, Nima Fadakar, Vahid Reza Ostovan, Abbas Rahimi-Jaberi, Nahid Ashjazadeh and 22 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 7 institutions in 5 countries.

Maryam Vasaghi GharamalekiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Maryam HabibagahiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Etrat HooshmandiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran. Electronic address: ehoshmandi@gmail.com.
Reza TabriziNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran; Clinical Research Development Unit, Vali Asr Hospital, University of Medical Sciences, Fasa, Iran.
Shahram Arsang-JangDepartment of Biostatistics and Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Zohreh BarzegarClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Nima FadakarClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Vahid Reza OstovanClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Abbas Rahimi-JaberiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Nahid AshjazadehClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Peyman PetramfarClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Maryam PoursadeghfardClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Sadegh IzadiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Masoumeh NazeriClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Hanieh BazrafshanClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Zahra BahramiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Sedigheh KarimluClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Seyedeh Shaghayegh ZafarmandClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Mahnaz BayatClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Mohammad Saied SalehiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Maryam OwjfardClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Saeideh Karimi-HaghighiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Anahid SafariClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Banafsheh ShakibajahromiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran.
Beng Lim Alvin ChewDepartment of Neurology, John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute, The University of Newcastle, Newcastle, Australia.
Bradford B G WorralDepartment of Neurology, University of Virginia, Charlottesville, VA, United States.
Jonathan M CoutinhoDepartment of Neurology, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherland.
Carlos Garcia-EsperonDepartment of Neurology, John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute, The University of Newcastle, Newcastle, Australia.
Neil SprattDepartment of Neurology, John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute, The University of Newcastle, Newcastle, Australia.
Christopher LeviDepartment of Neurology, John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute, The University of Newcastle, Newcastle, Australia.
Mahmoud Reza AzarpazhoohStroke Prevention and Atherosclerosis Research Center, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada; Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Afshin Borhani-HaghighiClinical Neurology Research Center, Shiraz University of Medical Sciences, P.O.Box: 7193635899, Shiraz, Iran; Department of Neurology, John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute, The University of Newcastle, Newcastle, Australia. Electronic address: neuro.ab@gmail.com.
Shiraz University of Medical Sciences · IRJohn Hunter Hospital · AUAmsterdam University Medical Centers · NLFasa University of Medical Sciences · IRUniversity of Virginia · USWestern University · CAZanjan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere are several reports of the association between SARS-CoV-2 infection (COVID-19) and cerebral venous sinus thrombosis (CVST). In this study, we aimed to compare the hospitalization rate of CVST before and during the COVID-19 pandemic (before vaccination program). MATERIALS AND

methodsIn this retrospective cohort study, the hospitalization rate of adult CVST patients in Namazi hospital, a tertiary referral center in the south of Iran, was compared in two periods of time. We defined March 2018 to March 2019 as the pre-COVID-19 period and March 2020 to March 2021 as the COVID-19 period.

results50 and 77 adult CVST patients were hospitalized in the pre-COVID-19 and COVID-19 periods, respectively. The crude CVST hospitalization rate increased from 14.33 in the pre-COVID-19 period to 21.7 per million in the COVID-19 era (P = 0.021). However, after age and sex adjustment, the incremental trend in hospitalization rate was not significant (95% CrI: -2.2, 5.14). Patients > 50-year-old were more often hospitalized in the COVID-19 period (P = 0.042). SARS-CoV-2 PCR test was done in 49.3% out of all COVID-19 period patients, which were positive in 6.5%. Modified Rankin Scale (mRS) score ≥3 at three-month follow-up was associated with age (P = 0.015) and malignancy (P = 0.014) in pre-COVID period; and was associated with age (P = 0.025), altered mental status on admission time (P<0.001), malignancy (P = 0.041) and COVID-19 infection (P = 0.008) in COVID-19 period.

conclusionSince there was a more dismal outcome in COVID-19 associated CVST, a high index of suspicion for CVST among COVID-19 positive is recommended.

Indexed as

COVID-19Sinus Thrombosis, IntracranialAdultHospitalizationHumansMiddle AgedPandemicsRetrospective StudiesSARS-CoV-2COVID-19Hospitalization ratePrognosisSARS-CoV-2Sinus thrombosisStroke

Identifiers

PMID35523051
PMCPMC8947940
OpenAlexW4225755242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.