Evidence map›Paper›PMID 35522567›Full record

ArticleeLife2022

Flexible utilization of spatial- and motor-based codes for the storage of visuo-spatial information.

Margaret M Henderson, Rosanne L Rademaker, John T Serences

Abstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sparse Spatial Scaffolding for Visual Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  7. Article
  8. Article
  9. Motor working memory.Trends in cognitive sciences · 2026
    Review
  10. Evidence for Abstract Codes in Parietal Cortex Guiding Prospective Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Sensory reformatting for a working visual memory.Trends in cognitive sciences · 2025
    Review
  15. Article
  16. Article
  17. Neural Dynamics of Reselecting Visual and Motor Contents in Working Memory after External Interference.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Margaret M HendersonNeurosciences Graduate Program, University of California, San Diego, San Diego, United States.ORCID 0000-0001-9375-6680
Rosanne L RademakerDepartment of Psychology, University of California, San Diego, San Diego, United States.
John T SerencesNeurosciences Graduate Program, University of California, San Diego, San Diego, United States.

Funding

The Distinction Between Number and Resolution in Visual Working MemoryR01MH087214 · NIMH · UNIVERSITY OF OREGON · PI AWH, EDWARD, VOGEL, EDWARD K · 2009 to 2023
$11.0M
TRAINING PROGRAM IN COGNITIVE NEUROSCIENCET32MH020002 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEJNOWSKI, TERRENCE J · 1999 to 2020
$6.1M
Adaptive population codes for flexible visually-guided behaviorsR01EY025872 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI John T Serences · 2016 to 2026
$4.5M
NEI NIH HHS R01 EY025872NIMH NIH HHS R01 MH087214NIMH NIH HHS T32 MH020002
6 · The paper itself

Abstract

Working memory provides flexible storage of information in service of upcoming behavioral goals. Some models propose specific fixed loci and mechanisms for the storage of visual information in working memory, such as sustained spiking in parietal and prefrontal cortex during working memory maintenance. An alternative view is that information can be remembered in a flexible format that best suits current behavioral goals. For example, remembered visual information might be stored in sensory areas for easier comparison to future sensory inputs, or might be re-coded into a more abstract action-oriented format and stored in motor areas. Here, we tested this hypothesis using a visuo-spatial working memory task where the required behavioral response was either known or unknown during the memory delay period. Using functional magnetic resonance imaging (fMRI) and multivariate decoding, we found that there was less information about remembered spatial position in early visual and parietal regions when the required response was known versus unknown. Furthermore, a representation of the planned motor action emerged in primary somatosensory, primary motor, and premotor cortex during the same task condition where spatial information was reduced in early visual cortex. These results suggest that the neural networks supporting working memory can be strategically reconfigured depending on specific behavioral requirements during a canonical visual working memory paradigm.

Indexed as

Memory, Short-TermMotor CortexBrain MappingMagnetic Resonance ImagingMental RecallParietal LobefMRIhumanmotor planningneural decodingneurosciencesensory recruitmentvisionworking memory

Identifiers

PMID35522567
PMCPMC9075954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.