Evidence map›Paper›PMID 35522426›Full record

ReviewCell proliferation2022

Human pluripotent stem cell registry: Operations, role and current directions.

Andreas Kurtz, Nancy Mah, Ying Chen, Antonie Fuhr, Sabine Kobold, Stefanie Seltmann, Sabine C Müller

Abstract readReview
In one paragraph

Review in Cell proliferation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andreas KurtzFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.ORCID https://orcid.org/0000-0003-3301-6546
Nancy MahFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
Ying ChenFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
Antonie FuhrFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
Sabine KoboldFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
Stefanie SeltmannFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
Sabine C MüllerFraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.

Funding

European Commission Horizon2020 037820European Commission Horizon2020 334502European Commission Horizon2020 726320
6 · The paper itself

Abstract

The human plutiripotent stem cell registry (hPSCreg) is a global database for human embryonic and induced pluripotent stem cells (hESC, hiPSC). The publicly accessible Registry (https://hpscreg.eu) was set up to provide a transparent resource of quality-assessed hPSC lines as well as to increase reproducibility of research and interoperability of data.

objectivesIn this review, we describe the establishment of the Registry and its mission, its development into a knowledgebase for hPSC and the current status of hPSC-focussed databases. The data categories available in hPSCreg are detailed. In addition, sharing and hurdles to data sharing on a global level are described.

conclusionsAn outlook is provided on the establishment of digital representatives of donors using hybrids of data and hPSC-based biological models, and how this can also be used to reposition databases as mediators between donors and researchers.

Indexed as

Induced Pluripotent Stem CellsPluripotent Stem CellsCell DifferentiationDatabases, FactualHumansRegistriesReproducibility of Results

Identifiers

PMID35522426
PMCPMC9357359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.