Evidence map›Paper›PMID 35522050›Full record

ArticleThe clinical respiratory journal2022

The relationship between absolute counts of lymphocyte subsets and clinical features in patients with pulmonary tuberculosis.

Hui-Ru An, Xue-Juan Bai, Jian-Qin Liang, Tao Wang, Zhong-Yuan Wang, Yong Xue, Yin-Ping Liu, Lan Wang, Xue-Qiong Wu

Open access · goldAbstract read
In one paragraph

Article in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hui-Ru AnDepartment of Tuberculosis, Senior Department of Tuberculosis, The Eighth Medical Center of PLA General Hospital, Beijing, China.
Xue-Juan BaiTuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute for Tuberculosis Research, Senior Department of Tuberculosis, 8th Medical Center of Chinese PLA General Hospital in China, Beijing, China.
Jian-Qin LiangDepartment of Tuberculosis, Senior Department of Tuberculosis, The Eighth Medical Center of PLA General Hospital, Beijing, China.
Tao WangDepartment of Tuberculosis, Senior Department of Tuberculosis, The Eighth Medical Center of PLA General Hospital, Beijing, China.
Zhong-Yuan WangDepartment of Tuberculosis, Senior Department of Tuberculosis, The Eighth Medical Center of PLA General Hospital, Beijing, China.
Yong XueTuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute for Tuberculosis Research, Senior Department of Tuberculosis, 8th Medical Center of Chinese PLA General Hospital in China, Beijing, China.
Yin-Ping LiuTuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute for Tuberculosis Research, Senior Department of Tuberculosis, 8th Medical Center of Chinese PLA General Hospital in China, Beijing, China.
Lan WangTuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute for Tuberculosis Research, Senior Department of Tuberculosis, 8th Medical Center of Chinese PLA General Hospital in China, Beijing, China.
Xue-Qiong WuTuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute for Tuberculosis Research, Senior Department of Tuberculosis, 8th Medical Center of Chinese PLA General Hospital in China, Beijing, China.
Beijing Chest Hospital · CNThe 309th Hospital of Chinese People's Liberation Army · CNCenter for Tuberculosis Control of Guangdong Province · CNChinese PLA General Hospital · CN

Funding

Key Project of The Eighth Medical Center of PLA General Hospital in China 2018ZD-005Medical Innovation Project 18CXZ028Serious Infectious Diseases Special Foundation of China 2012ZX10003008002Serious Infectious Diseases Special Foundation of China 2017ZX10201301-007-001
6 · The paper itself

Abstract

backgroundThe aim of the present study is to investigate the clinical value and characteristics of peripheral blood lymphocyte subsets in patients with pulmonary tuberculosis (PTB) using flow cytometry.

methodsThe absolute counts of T, CD4

resultsIn 75.3% of the patients with PTB, six subset counts were lower than the normal reference range, and 44% showed lower-than-normal CD4

conclusionsIn most patients with tuberculosis, immune function is impaired. The absolute counts of peripheral blood lymphocyte subsets are closely related to the aetiological results and lesion severity in patients with PTB; this could be used as evidence for immune intervention and monitoring curative effects.

Indexed as

Lymphocyte SubsetsTuberculosis, PulmonaryB-LymphocytesFemaleHumansLymphocyte CountMaleT-LymphocytesT-Lymphocyte Subsetsabsolute countsflow cytometryimmunitylymphocyte subsetspulmonary tuberculosis

Identifiers

PMID35522050
PMCPMC9366570
OpenAlexW4229026358

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.