ArticleThe Plant cell2022
Progressive chromatin silencing of ABA biosynthesis genes permits seed germination in Arabidopsis.
Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Seed priming with Streptomyces griseoviridis culture filtrate: species-specific enhancement of legume germination and seedling vigor through hormonal and metabolic signaling.BMC plant biology · 2026Article
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- Advances in seed omics.Journal of experimental botany · 2026Review
- Phytochrome B stabilizes the KNOX transcription factor BP/KNAT1 to promote light-initiated seed germination in Arabidopsis thaliana.Plant communications · 2025Article
- Fluctuations in nitrate availability impact cytokinin biosynthesis through histone modifications of IPT3 in Arabidopsis roots for growth acclimation.Plant communications · 2025Article
- ODR1/AtSDR4L alleviates osmotic stress-induced germination arrest via ABA-dependent negative feedback on ABA biosynthesis.BMC plant biology · 2025Article
- Comprehensive Analysis ofBiology · 2025Article
- Synergistic effects of Fe nanocomplex and nitrophenolate-based biostimulant on growth and physiological performance of tomato seedlings.BMC plant biology · 2025Article
- Genome-Wide Identification of thePlants (Basel, Switzerland) · 2025Article
- Control of seed-to-seedling transition by an upstream open reading frame inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025Review
- PlZAT10 binds to the ABA catabolism gene PlCYP707A2 promoter to mediate seed dormancy release in Paeonia lactiflora.Plant cell reports · 2024Article
- Seed longevity and genome damage.Bioscience reports · 2024Review
- Voice from both sides: a molecular dialogue between transcriptional activators and repressors in seed-to-seedling transition and crop adaptation.Frontiers in plant science · 2024Review
- Transcriptome analysis reveals the molecular mechanisms of rubber biosynthesis and laticifer differentiation during rubber seed germination.Frontiers in plant science · 2024Article
- A Travel through Landscapes of Seed Dormancy.Plants (Basel, Switzerland) · 2023Review
- MADS-box protein PpDAM6 regulates chilling requirement-mediated dormancy and bud break in peach.Plant physiology · 2023Article
- A VEL3 histone deacetylase complex establishes a maternal epigenetic state controlling progeny seed dormancy.Nature communications · 2023Article
- Better to keep silent: Chromatin-mediated repression of ABA biosynthesis and signaling genes allows seed germination.The Plant cell · 2022Article
- Mild and severe salt stress responses are age-dependently regulated by abscisic acid in tomato.Frontiers in plant science · 2022Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seed germination represents a major developmental switch in plants that is vital to agriculture, but how this process is controlled at the chromatin level remains obscure. Here we demonstrate that successful germination in Arabidopsis thaliana requires a chromatin mechanism that progressively silences 9-CIS-EPOXYCAROTENOID DIOXYGENASE 6 (NCED6), which encodes a rate-limiting enzyme in abscisic acid (ABA) biosynthesis, through the cooperative action of the RNA-binding protein RZ-1 and the polycomb repressive complex 2 (PRC2). Simultaneous inactivation of RZ-1 and PRC2 blocked germination and synergistically derepressed NCEDs and hundreds of genes. At NCED6, in part by promoting H3 deacetylation and suppressing H3K4me3, RZ-1 facilitates transcriptional silencing and also an H3K27me3 accumulation process that occurs during seed germination and early seedling growth. Genome-wide analysis revealed that RZ-1 is preferentially required for transcriptional silencing of many PRC2 targets early during seed germination, when H3K27me3 is not yet established. We propose RZ-1 confers a novel silencing mechanism to compensate for and synergize with PRC2. Our work highlights the progressive chromatin silencing of ABA biosynthesis genes via the RNA-binding protein RZ-1 and PRC2 acting in synergy, a process that is vital for seed germination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.