Evidence map›Paper›PMID 35521657›Full record

ArticleThyroid : official journal of the American Thyroid Association2022

A Pilot Study of Durvalumab (MEDI4736) with Tremelimumab in Combination with Image-Guided Stereotactic Body Radiotherapy in the Treatment of Metastatic Anaplastic Thyroid Cancer.

Nancy Y Lee, Nadeem Riaz, Vanessa Wu, Thomas Brinkman, Chiaojung J Tsai, Wanquing Zhi, James Fetten, Alan Ho, Richard J Wong, Ronald Ghossein and 4 more

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Innovative immunotherapeutic strategies for thyroid cancer: challenges and opportunities.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  16. Aggressive Types of Malignant Thyroid Neoplasms.Journal of clinical medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Nancy Y LeeDepartment of Radiation Oncology, MSKCC, New York, New York, USA.
Nadeem RiazDepartment of Radiation Oncology, MSKCC, New York, New York, USA.
Vanessa WuDepartment of Radiation Oncology, MSKCC, New York, New York, USA.
Thomas BrinkmanDepartment of Radiation Oncology, MSKCC, New York, New York, USA.
Chiaojung J TsaiDepartment of Radiation Oncology, MSKCC, New York, New York, USA.
Wanquing ZhiDivision of Head and Neck Medical Oncology, Department of Medicine, MSKCC, New York, New York, USA.ORCID 0000-0003-4263-7272
James FettenDivision of Head and Neck Medical Oncology, Department of Medicine, MSKCC, New York, New York, USA.
Alan HoDivision of Head and Neck Medical Oncology, Department of Medicine, MSKCC, New York, New York, USA.ORCID 0000-0002-6885-3742
Richard J WongDepartment of Surgery, MSKCC, New York, New York, USA.
Ronald GhosseinDepartment of Pathology, MSKCC, New York, New York, USA.
Michael TuttleEndocrine Service, Department of Medicine, MSKCC, New York, New York, USA.
James FaginEndocrine Service, Department of Medicine, MSKCC, New York, New York, USA.ORCID 0000-0002-2365-2517
David G PfisterDivision of Head and Neck Medical Oncology, Department of Medicine, MSKCC, New York, New York, USA.
Eric ShermanDivision of Head and Neck Medical Oncology, Department of Medicine, MSKCC, New York, New York, USA.
New York Oncology Hematology · USDiabetes & Endocrine Associates · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016042
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

RadiosurgeryThyroid Carcinoma, AnaplasticThyroid NeoplasmsAgedAged, 80 and overAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic Combined Chemotherapy ProtocolsHumansMaleMiddle AgedPilot ProjectsAntibodies, MonoclonalAntibodies, Monoclonal, Humanizeddurvalumabtremelimumabanaplastic thyroid cancerimmunotherapySBRT

Identifiers

PMID35521657
PMCPMC9293682
OpenAlexW4229002024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.