Evidence map›Paper›PMID 35521564›Full record

ArticleRSC advances2018

A targeted biocompatible organic nanoprobe for photoacoustic and near-infrared-II fluorescence imaging in living mice.

Xinhui Xie, Yili Hu, Chao Zhang, Jialei Song, Suyang Zhuang, Yuntao Wang

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Recent Progress of Near-Infrared Fluorescence in vivo Bioimaging in the Second and Third Biological Window.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinhui XieThe Department of Orthopedics, Zhong Da Hospital, School of Medicine, Southeast University Nanjing Jiangsu 210009 China xiexinghuixxh@163.com.
Yili HuThe Department of Orthopedics, Zhong Da Hospital, School of Medicine, Southeast University Nanjing Jiangsu 210009 China xiexinghuixxh@163.com.
Chao ZhangCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University Nanjing Jiangsu 210093 China.ORCID https://orcid.org/0000-0003-4580-1381
Jialei SongThe Department of Orthopedics, Zhong Da Hospital, School of Medicine, Southeast University Nanjing Jiangsu 210009 China xiexinghuixxh@163.com.
Suyang ZhuangThe Department of Orthopedics, Zhong Da Hospital, School of Medicine, Southeast University Nanjing Jiangsu 210009 China xiexinghuixxh@163.com.
Yuntao WangThe Department of Orthopedics, Zhong Da Hospital, School of Medicine, Southeast University Nanjing Jiangsu 210009 China xiexinghuixxh@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multimodal molecular imaging probes have attracted much attention, and they possess great potential to accurately diagnose diseases due to the synergistic superiorities of multiple complementary imaging. Herein, a targeted biocompatible organic nanoplatform (IR-PEG-FA) with a strong optical absorption in the near-infrared window (NIR-I) for photoacoustic imaging (PAI) and excellent second near-infrared (NIR-II) fluorescence imaging property for NIR-II imaging is fabricated. The dual-modal nanoprobe is composed of the small organic dye molecule IR-1061, water-soluble poly(ethylene glycol) (PEG) and folic acid (FA) as the targeted ligands. Depending on the strength of high temporal resolution and preeminent spatial resolution, the targeted biocompatible dual-mode nanoprobe for PAI and NIR-II imaging can provide more detailed date of cancers and diseases, and enables us to specifically diagnose them through quite a precise way.

Identifiers

PMID35521564
PMCPMC9059267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.