Evidence map›Paper›PMID 35521519›Full record

ArticleiScience2022

Calcium carbonate mineralization is essential for biofilm formation and lung colonization.

Malena Cohen-Cymberknoh, Dror Kolodkin-Gal, Alona Keren-Paz, Shani Peretz, Vlad Brumfeld, Sergey Kapishnikov, Ronit Suissa, Michal Shteinberg, Daniel McLeod, Harsh Maan and 4 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Calcium regulation ofApplied and environmental microbiology · 2026
    Article
  2. How bacteria actively use passive physics to make biofilms.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. A laboratory perspective onFrontiers in microbiology · 2024
    Review
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Malena Cohen-CymberknohPediatric Pulmonary Unit and Cystic fibrosis Center, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel.
Dror Kolodkin-GalDepartment of Experimental Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Alona Keren-PazDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Shani PeretzDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Vlad BrumfeldChemical Research Support, Weizmann Institute of Science, Rehovot, Israel.
Sergey KapishnikovChemical Research Support, Weizmann Institute of Science, Rehovot, Israel.
Ronit SuissaDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Michal ShteinbergPulmonology Institute and CF Center, Carmel Medical Center, Haifa, Israel.
Daniel McLeodDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA.
Harsh MaanDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Marianna PatrauchanDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA.
Gideon ZamirDepartment of Experimental Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Eitan KeremPediatric Pulmonary Unit and Cystic fibrosis Center, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel.
Ilana Kolodkin-GalDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Weizmann Institute of Science · ILHadassah Medical Center · ILOklahoma State University · USCarmel Medical Center · ILHebrew University of Jerusalem · IL

Funding

ZFC3H1 Regulation of Host Defense and Influenza A Virus PathogenesisP20GM103648 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI CHENG, YONG · 2013 to 2022
$22.3M
Calcium signaling controls Pseudomonas aeruginosa invasion and adaptation to the host intracellular environmentR15GM124670 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI PATRAUCHAN, MARIANNA M. A. · 2017 to 2023
$1.1M
NIGMS NIH HHS P20 GM103648NIGMS NIH HHS R15 GM124670
6 · The paper itself

Abstract

Biofilms are differentiated microbial communities held together by an extracellular matrix. μCT X-ray revealed structured mineralized areas within biofilms of lung pathogens belonging to two distant phyla - the proteobacteria

Indexed as

Cell biologyMicrobiofilmsMicrobiology

Identifiers

PMID35521519
PMCPMC9062676
OpenAlexW4223582909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.