Evidence map›Paper›PMID 35521457›Full record

ArticleRSC advances2020

Laminin-modified gellan gum hydrogels loaded with the nerve growth factor to enhance the proliferation and differentiation of neuronal stem cells.

Wenqiang Li, Anfei Huang, Yanheng Zhong, Lin Huang, Jing Yang, Changren Zhou, Lin Zhou, Yanling Zhang, Guo Fu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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  13. Development of epimedin A complex drugs for treating the osteoporosis.Journal of materials science. Materials in medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Wenqiang LiEngineering Technology Research Center for Sports Assistive Devices of Guangdong, Guangzhou Sport University Guangzhou China.ORCID https://orcid.org/0000-0002-1498-2258
Anfei HuangThe First Affiliated Hospital, Jinan University Guangzhou China hyzhoulin@126.com dr.fuguo@qq.com.
Yanheng ZhongThe First Affiliated Hospital, Jinan University Guangzhou China hyzhoulin@126.com dr.fuguo@qq.com.
Lin HuangEngineering Technology Research Center for Sports Assistive Devices of Guangdong, Guangzhou Sport University Guangzhou China.
Jing YangEngineering Technology Research Center for Sports Assistive Devices of Guangdong, Guangzhou Sport University Guangzhou China.
Changren ZhouDepartment of Materials Science and Engineering, Jinan University Guangzhou China.
Lin ZhouThe First Affiliated Hospital, Jinan University Guangzhou China hyzhoulin@126.com dr.fuguo@qq.com.
Yanling ZhangDepartment of Ultrasound, Third Affiliated Hospital, Sun Yat-sen University The People's Republic of China 15136102@qq.com.ORCID https://orcid.org/0000-0003-3496-1822
Guo FuThe First Affiliated Hospital, Jinan University Guangzhou China hyzhoulin@126.com dr.fuguo@qq.com.
First Affiliated Hospital of Jinan University · CNGuangzhou Sport University · CNJinan University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reconstruction of peripheral nerves has lately received great attention as many patients suffer from peripheral nerve injury every year around the world. However, the damage to human nerve cells has different degrees of irreversibility due to a slow growth speed and low adhesion with the surrounding tissues. In an effort to overcome this challenge, we applied novel laminin (LN)-modified thiolated gellan gum (TGG) and loaded the nerve growth factor (NGF) as a tissue engineering scaffold for facilitating neuronal stem cell proliferation

Identifiers

PMID35521457
PMCPMC9053442
OpenAlexW3021274238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.