Evidence map›Paper›PMID 35521362›Full record

ArticleEnvironmental health insights2022

Urinary Pesticide Residual Levels and Acute Respiratory Infections in Children Under 5 Years of Age: Findings From the Offinso North Farm Health Study.

Enoch Akyeampong, John R Bend, Isaac Luginaah, David Oscar Yawson, Samuel Jerry Cobbina, Frederick Ato Armah, Michael Osei Adu, David Kofi Essumang, Samuel Iddi, Paul K Botwe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Environmental health insights, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Alterations in murine macrophage reactivity and bactericidal efficacy following exposure to an environmentally relevant mixture of organochlorine pesticide compounds.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2025
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Enoch AkyeampongBiological, Environmental & Occupational Health Sciences, School of Public Health, University of Ghana, Legon, Accra, Ghana.
John R BendDepartment of Pathology & Laboratory Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Isaac LuginaahDepartment of Geography, Western University, London, ON, Canada.
David Oscar YawsonCentre for Resource Management and Environmental Studies (CERMES), The University of the West Indies, Bridgetown, St. Michael, Barbados.
Samuel Jerry CobbinaDepartment of Ecotourism and Environmental Management, Faculty of Natural Resources and Environment, University for Development Studies, Nyankpala, Ghana.
Frederick Ato ArmahDepartment of Environmental Science, School of Biological Sciences, College of Agriculture & Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
Michael Osei AduDepartment of Crop Science, School of Agriculture, College of Agriculture & Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
David Kofi EssumangEnvironmental Research Group, Department of Chemistry, School of Physical Sciences, University of Cape Coast, Ghana.ORCID https://orcid.org/0000-0002-0589-7895
Samuel IddiDepartment of Statistics and actuarial science, University of Ghana, Legon, Accra, Ghana.
Paul K BotweBiological, Environmental & Occupational Health Sciences, School of Public Health, University of Ghana, Legon, Accra, Ghana.
Reginald QuansahBiological, Environmental & Occupational Health Sciences, School of Public Health, University of Ghana, Legon, Accra, Ghana.ORCID https://orcid.org/0000-0002-7318-4192
University of Ghana · GHUniversity of Cape Coast · GHWestern University · CAUniversity for Development Studies · GHUniversity of the West Indies · BB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several environmental factors are associated with the risk of acute lower respiratory infections (ALRIs) and upper respiratory infections (URIs) in children under 5 years of age (YOA). Evidence implicating chemical pesticides remains equivocal. There are also no data on this subject in these children in Ghana. This study investigated the association between urinary pesticide residual levels and the risk for ALRIs/URIs in children under 5 YOA. Methods: The participants for this study were from the Offinso North Farm Health Study, a population-based cross-sectional study. Two hundred and fifty four parents/guardians who had answered affirmatively to the question "Has your child ever accompanied you to the farm?" were interviewed on household socio-demographic and environmental factors, being breastfed, child education, age, gender, and respiratory infection. One hundred fifty children were randomly selected to provide the first void urine. Results: The proportion of children with ALRI was 22.1% and those with URI was 35.8%. We observed a statistically significant exposure-response relation of p,p'-DDE (tertile) with ALRI (1.7-3.2 µg/L urine: prevalence ratio [PR] = 1.22 [1.05-1.70], ⩾3.2 µg/L urine: 1.50 [1.07-3.53] [ Conclusions: The present study supports the hypothesis that exposure to chemical pesticides is associated with respiratory infections in children under 5 YOA.

Indexed as

children under 5 years of ageGhanaOffinso North Districtrespiratory infectionurinary pesticides residual levels

Identifiers

PMID35521362
PMCPMC9067049
OpenAlexW4285254964

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.