Evidence map›Paper›PMID 35521317›Full record

ArticleRSC advances2019

Solidly mounted resonator sensor for biomolecule detections.

Chengzhang Han, Xia Wang, Qiuling Zhao, Lihua Teng, Shuaiyi Zhang, Hao Lv, Jing Liu, Haoran Ma, Yanping Wang

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chengzhang HanOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.ORCID https://orcid.org/0000-0002-6546-9825
Xia WangOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Qiuling ZhaoOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Lihua TengOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Shuaiyi ZhangOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Hao LvOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Jing LiuOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Haoran MaOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.
Yanping WangOptoelectronic Materials and Technologies Engineering Laboratory, Shandong, Physics Department, Qingdao University of Science and Technology Qingdao 266042 China phwangxia@163.com sdqlzhao@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the fabrication of a solidly mounted resonator (SMR) that can also function as a sensor for biological molecules. The SMR, consisting of a Au electrode, aluminum nitride (AlN) piezoelectric thin film and Bragg acoustic reflector, was fabricated on a Si substrate by radio frequency (RF) magnetron sputtering. The Bragg acoustic reflector, made entirely of metal, has small internal stress and good heat conduction. Human immunoglobulin G (IgG) antibody was immobilized on the modified (by self-assembled monolayer method) Au electrode surface of the SMR and goat anti-human IgG antigen was captured through the specificity of bond between the antibody and antigen on the electrode surface. We found a linear relationship between the resonant frequency shift and the concentration of goat anti-human IgG antigen for concentrations smaller than 0.4 mg ml

Identifiers

PMID35521317
PMCPMC9065989

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.